Human β-secretase (BACE) and BACE inhibitors

[11] Freskos J. N., 2002, [No title captured], Patent No. [02098849, WO 02/098849]

[12] Gailunas A., 2003, [No title captured], Patent No. [03027068, WO 03/027068]

[13] GAILUNAS A, 2003, Patent No. 0300642

[14] Structure-based design:: Potent inhibitors of human brain memapsin 2 (β-secretase) [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (18) : 2865 - 2868

[15] ALZHEIMERS-DISEASE - INITIAL REPORT OF THE PURIFICATION AND CHARACTERIZATION OF A NOVEL CEREBROVASCULAR AMYLOID PROTEIN [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (03) : 885 - 890

[16] Hom R., 2001, [No title captured], Patent No. [WO 01/070672, 01070672]

[17] Design and synthesis of statine-based cell-permeable peptidomimetic inhibitors of human β-secretase [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2003, 46 (10) : 1799 - 1802

[18] Structure of the protease domain of memapsin 2 (β-secretase) complexed with inhibitor [J]. SCIENCE, 2000, 290 (5489) : 150 - 153

[19] Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme -: The Alzheimer's disease β-secretase [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (43) : 33729 - 33737

[20] John V., 2003, [No title captured], Patent No. [03002122, WO 03/002122]

[11] Freskos J. N., 2002, [No title captured], Patent No. [02098849, WO 02/098849]

[12] Gailunas A., 2003, [No title captured], Patent No. [03027068, WO 03/027068]

[13] GAILUNAS A, 2003, Patent No. 0300642

[14] Structure-based design:: Potent inhibitors of human brain memapsin 2 (β-secretase) [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (18) : 2865 - 2868

[15] ALZHEIMERS-DISEASE - INITIAL REPORT OF THE PURIFICATION AND CHARACTERIZATION OF A NOVEL CEREBROVASCULAR AMYLOID PROTEIN [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1984, 120 (03) : 885 - 890

[16] Hom R., 2001, [No title captured], Patent No. [WO 01/070672, 01070672]

[17] Design and synthesis of statine-based cell-permeable peptidomimetic inhibitors of human β-secretase [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2003, 46 (10) : 1799 - 1802

[18] Structure of the protease domain of memapsin 2 (β-secretase) complexed with inhibitor [J]. SCIENCE, 2000, 290 (5489) : 150 - 153

[19] Maturation and endosomal targeting of β-site amyloid precursor protein-cleaving enzyme -: The Alzheimer's disease β-secretase [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (43) : 33729 - 33737

[20] John V., 2003, [No title captured], Patent No. [03002122, WO 03/002122]