Bioactive sesquiterpenes from a Taiwanese marine sponge Parahigginsia sp.

被引：28

作者：

Chen, CY ^{[1
]}

Shen, YC ^{[1
]}

Chen, YJ ^{[1
]}

Sheu, JH ^{[1
]}

Duh, CY ^{[1
]}

机构：

[1] Natl Sun Yat Sen Univ, Inst Marine Resources, Kaohsiung 80424, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 1999年 / 62卷 / 04期

关键词：

D O I：

10.1021/np980491p

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Five new sesquiterpenes, parahigginols A-D (1-4) and parahigginic acid (5), have been isolated from a Taiwanese marine sponge Parahigginsia sp. The structural assignments of the new compounds were based on their spectral data, including 1D and 2D NMR. Biological studies revealed that compounds 2-5 exhibited cytotoxicity against murine P-388 and human KB16, A549, and HT-29 tumor cells.

引用

页码：573 / 576

页数：4

共 10 条

[1]

Chen Y.-C., COMMUNICATION

[2] (+)-CURCUPHENOL AND DEHYDROCURCUPHENOL, NOVEL SESQUITERPENES WHICH INHIBIT H,K-ATPASE, FROM A MARINE SPONGE EPIPOLASIS SP [J].

FUSETANI, N ;

SUGANO, M ;

MATSUNAGA, S ;

HASHIMOTO, K .

EXPERIENTIA, 1987, 43 (11-12) :1234-1235

[3] STRUCTURES AND SYNTHESIS OF SOME NEW ANTIBACTERIAL SESQUITERPENOIDS FROM GORGONIAN CORAL PSEUDOPTEROGORGIA-RIGIDA [J].

MCENROE, FJ ;

FENICAL, W .

TETRAHEDRON, 1978, 34 (11) :1661-1664

[4] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS [J].

MOSMANN, T .

JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) :55-63

[5]

National Archives and Record Service Oral History Project, COMMUNICATION

[6]

Shen Ya-Ching, 1995, Journal of the Fisheries Society of Taiwan, V22, P365

[7]

Shen Ya-Ching, 1997, Journal of the Fisheries Society of Taiwan, V24, P117

[8]

Shen Ya-Ching, 1996, Chinese Pharmaceutical Journal, V48, P1

[9] New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis [J].

Shen, YC ;

Hsieh, PW .

JOURNAL OF NATURAL PRODUCTS, 1997, 60 (02) :93-97

[10]

SOCTT AI, 1964, INTERPRETATION ULTRA, P91

← 1 →