Noninvasive ventilation reduces mortality in acute respiratory failure following lung resection

被引：255

作者：

Auriant, I ^{[1
]}

Jallot, A ^{[1
]}

Hervé, P ^{[1
]}

Cerrina, J ^{[1
]}

Ladurie, FL ^{[1
]}

Fournier, JL ^{[1
]}

Lescot, B ^{[1
]}

Parquin, F ^{[1
]}

机构：

[1] Marie Lannelongue Surg Ctr, Surg Intens Care Unit, Surg Resp ICU, F-92350 Le Plessis Robinson, France

来源：

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2001年 / 164卷 / 07期

关键词：

noninvasive ventilation; acute hypoxemic respiratory insufficiency; endotracheal intubation; invasive mechanical ventilation; lung resection;

D O I：

10.1164/ajrccm.164.7.2101089

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

When treated with invasive endotracheal mechanical ventilation (ETMV), acute respiratory insufficiency after lung resection is fatal in up to 80% of cases. Noninvasive positive-pressure ventilation (NPPV) may reduce the need for ETMV, thereby improving survival. We conducted a randomized prospective trial to compare standard therapy with and without nasal-mask NPPV in patients with acute hypoxemic respiratory insufficiency after lung resection. The primary outcome variable was the need for ETMV and the secondary outcome variables were in-hospital and 120-d mortality rates, duration of stay in the intensive care unit, and duration of in-hospital stay. Twelve of the 24 patients (50%) randomly assigned to the no-NPPV group required ETMV, versus only five of the 24 patients (20.8%) in the NPPV group (p = 0.035). Nine patients in the no-NPPV group died (37.5%), and three (12.5%) patients in the NPPV group died (p = 0.045). The other secondary outcomes were similar in the two groups. NPPV is safe and effective in reducing the need for ETMV and improving survival after lung resection.

引用

页码：1231 / 1235

页数：5

共 25 条

[1] A comparison of noninvasive positive-pressure ventilation and conventional mechanical ventilation in patients with acute respiratory failure [J].