Leukocytes in Mammary Development and Cancer

被引：148

作者：

Coussens, Lisa M. ^{[2
,3
]}

Pollard, Jeffrey W. ^{[1
]}

机构：

[1] Albert Einstein Coll Med, Dept Obstet & Gynecol & Womens Hlth, Dept Dev & Mol Biol, Ctr Study Reprod Biol & Womens Hlth, New York, NY 10461 USA

[2] Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2011年 / 3卷 / 03期

关键词：

TUMOR-ASSOCIATED MACROPHAGES; STIMULATING FACTOR-I; ENDOTHELIAL GROWTH-FACTOR; GENE-EXPRESSION ANALYSIS; CD4(+) T-CELLS; ANGIOGENIC SWITCH; GLAND DEVELOPMENT; BREAST-CANCER; MOUSE MODEL; MAST-CELLS;

D O I：

10.1101/cshperspect.a003285

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Leukocytes, of both the innate and adaptive lineages, are normal cellular components of all tissues. These important cells not only are critical for regulating normal tissue homeostasis, but also are significant paracrine regulators of all physiologic and pathologic tissue repair processes. This article summarizes recent insights regarding the trophic roles of leukocytes at each stage of mammary gland development and during cancer development, with a focus on Murids and humans.

引用

收藏

页码：1 / 22

页数：22

相关论文

共 148 条

[31] Paradoxical roles of the immune system during cancer development [J].

de Visser, KE ;

Eichten, A ;

Coussens, LM .

NATURE REVIEWS CANCER, 2006, 6 (01) :24-37

[32] Inflammation and breast cancer - Balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression [J].

DeNardo, David G. ;

Coussens, Lisa M. .

BREAST CANCER RESEARCH, 2007, 9 (04)

[33] CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages [J].

DeNardo, David G. ;

Barreto, Jairo B. ;

Andreu, Pauline ;

Vasquez, Lesley ;

Tawfik, David ;

Kolhatkar, Nikita ;

Coussens, Lisa M. .

CANCER CELL, 2009, 16 (02) :91-102

[34]

DISIS ML, 1994, CANCER RES, V54, P16

[35]

Djonov V, 2001, MICROSC RES TECHNIQ, V52, P182, DOI 10.1002/1097-0029(20010115)52:2<182::AID-JEMT1004>3.0.CO

[36]

2-M

[37] New functions for the matrix metalloproteinases in cancer progression [J].

Egeblad, M ;

Werb, Z .

NATURE REVIEWS CANCER, 2002, 2 (03) :161-174

[38] Latent transforming growth factor-β activation in mammary gland -: Regulation by ovarian hormones affects ductal and alveolar proliferation [J].

Ewan, KB ;

Shyamala, G ;

Ravani, SA ;

Tang, Y ;

Akhurst, R ;

Wakefield, L ;

Barcellos-Hoff, MH .

AMERICAN JOURNAL OF PATHOLOGY, 2002, 160 (06) :2081-2093

[39] Stromal gene expression predicts clinical outcome in breast cancer [J].

Finak, Greg ;

Bertos, Nicholas ;

Pepin, Francois ;

Sadekova, Svetlana ;

Souleimanova, Margarita ;

Zhao, Hong ;

Chen, Haiying ;

Omeroglu, Gulbeyaz ;

Meterissian, Sarkis ;

Omeroglu, Atilla ;

Hallett, Michael ;

Park, Morag .

NATURE MEDICINE, 2008, 14 (05) :518-527

[40] Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells [J].

Gallina, Giovanna ;

Dolcetti, Luigi ;

Serafini, Paolo ;

De Santo, Carmela ;

Marigo, Ilaria ;

Colombo, Mario P. ;

Basso, Giuseppe ;

Brombacher, Frank ;

Borrello, Ivan ;

Zanovello, Paola ;

Bicciato, Silvio ;

Bronte, Vincenzo .

JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (10) :2777-2790

← 1 2 3 4 5 6 7 8 9 10 →