Synthesis and complete assignment of NMR data of 20 chalcones

被引:47
作者
Hwang, Doseok
Hyun, Jiye
Jo, Geunhyeong
Koh, Dongsoo [2 ]
Lim, Yoongho [1 ]
机构
[1] Konkuk Univ, Dept Biosci & Biotechnol, Bio Mol Informat Ctr, Kwangjin Ku, Seoul 143701, South Korea
[2] Dongduk Womens Univ, Dept Appl Chem, Seoul 136714, South Korea
关键词
NMR; H-1; C-13; 2D NMR; flavonoid; chalcone;
D O I
10.1002/mrc.2707
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
Chalcones, intermediates in flavonoid biosynthesis, can exhibit antibacterial, antiproliferative, and anti-inflammatory properties. Chalcones contain two benzene rings and both hydroxylated and methoxylated analogs are frequently produced by hydroxylases and O-methyltransferases in plant biosynthetic pathways. Assignments of NMR peaks in the spectra of hydroxylated and/or methoxylated chalcones can help in identifying novel chalcone derivatives isolated from natural sources by referencing these data against NMR spectra obtained from known chalcones. We report here the syntheses of 20 chalcones and complete assignments of H-1 and C-13 NMR spectra. Copyright (C) 2010 John Wiley & Sons, Ltd.
引用
收藏
页码:41 / 45
页数:5
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