Blood, sweat, and tears: developing clinically relevant protein biosensors for integrated body fluid analysis

被引：148

作者：

Corrie, S. R. ^{[1
,2
,3
]}

Coffey, J. W. ^{[1
,3
]}

Islam, J. ^{[1
,3
]}

Markey, K. A. ^{[4
,5
]}

Kendall, M. A. F. ^{[1
,2
,3
,6
]}

机构：

[1] Univ Queensland, Australian Inst Bioengn & Nanotechnol, Delivery Drugs & Genes Grp D2G2, St Lucia, Qld 4072, Australia

[2] Australian Infect Dis Res Ctr, St Lucia, Qld 4067, Australia

[3] Univ Queensland, ARC Ctr Excellence Convergent Bionano Sci & Techn, St Lucia, Qld 4072, Australia

[4] QIMR Berghofer Med Res Inst, Herston, Qld 4006, Australia

[5] Princess Alexandra Hosp, Dept Hematol, Brisbane, Qld 4029, Australia

[6] Univ Queensland, Fac Med & Biomed Sci, St Lucia, Qld 4072, Australia

来源：

ANALYST | 2015年 / 140卷 / 13期

基金：

英国医学研究理事会; 澳大利亚研究理事会;

关键词：

POINT-OF-CARE; EXHALED BREATH CONDENSATE; CRYSTALLINE BIOFILM FORMATION; MONITOR MUTANS STREPTOCOCCI; SUCTION BLISTER FLUID; CEREBROSPINAL-FLUID; ALPHA-AMYLASE; CONTACT-LENS; HUMAN SALIVA; URIC-ACID;

D O I：

10.1039/c5an00464k

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Biosensors are being developed to provide rapid, quantitative, diagnostic information to clinicians in order to help guide patient treatment, without the need for centralised laboratory assays. The success of glucose monitoring is a key example of where technology innovation has met a clinical need at multiple levels from the pathology laboratory all the way to the patient's home. However, few other biosensor devices are currently in routine use. Here we review the challenges and opportunities regarding the integration of biosensor techniques into body fluid sampling approaches, with emphasis on the point-of-care setting.

引用

页码：4350 / 4364

页数：15

共 176 条

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