Organ preservation for carcinoma of the larynx and hypopharynx

被引:15
作者
Garden, AS [1 ]
机构
[1] Univ Texas, MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA
关键词
D O I
10.1016/S0889-8588(05)70210-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Treatment of laryngeal and hypopharyngeal cancers often necessitates total laryngectomy. This article reviews approaches of curing patients with these diseases while preserving their larynxes. Strategies include radiation alone, neoadjuvant chemotherapy with radiation for responders, or concurrent chemotherapy and radiation. Both retrospective experiences and randomized trials evaluating differing therapies in an effort to achieve voice preservation are reported and analyzed.
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页码:243 / +
页数:19
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