Membrane traffic: How do GGAs fit in with the adaptors?

被引：11

作者：

Black, MW ^{[1
]}

Pelham, HRB ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 12期

关键词：

D O I：

10.1016/S0960-9822(01)00281-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The AP-1 adaptor complex has been cast as the major player in clathrin coat formation for vesicular transpirt from the trans-Golgi to the endocytic pathway. But new results on 'GGA' proteins have raised doubts about this paradigm and suggest both a new sorting mechanism and an unexpected complexity in the roles of clathrin. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：R460 / R462

页数：3