共 22 条
Membrane traffic: How do GGAs fit in with the adaptors?
被引:11
作者:
Black, MW
[1
]
Pelham, HRB
[1
]
机构:
[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
关键词:
D O I:
10.1016/S0960-9822(01)00281-0
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The AP-1 adaptor complex has been cast as the major player in clathrin coat formation for vesicular transpirt from the trans-Golgi to the endocytic pathway. But new results on 'GGA' proteins have raised doubts about this paradigm and suggest both a new sorting mechanism and an unexpected complexity in the roles of clathrin. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码:R460 / R462
页数:3
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