Non-linear effects operate and dynamic ligand exchange occurs when chiral BINOL-boron Lewis acids are used for asymmetric catalysis

被引：21

作者：

Cros, JP ^{[1
]}

Peréz-Fuertes, Y ^{[1
]}

Thatcher, MJ ^{[1
]}

Arimori, S ^{[1
]}

Bull, SD ^{[1
]}

James, TD ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

来源：

TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 14期

关键词：

D O I：

10.1016/S0957-4166(03)00352-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Non-linear effects reveal that the use of chiral BINOL-boron reagents for aza-Diels-Alder reactions results in an enantioselective catalytic species containing at least 2 equiv. of BINOL. Dynamic ligand exchange and ligand accelerated catalysis occurs in these reactions, consistent with the formation of a cyclic borate ester of BINOL with enhanced Lewis acidity. (C) 2003 Elsevier Science Ltd. All rights reserved.

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页码：1965 / 1968

页数：4

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