Primate adult brain cell autotransplantation, a new tool for brain repair?

被引：18

作者：

Brunet, JF

Rouiller, E

Wannier, T

Villemure, JG

Bloch, J

机构：

[1] Univ Fribourg, Inst Physiol, Dept Med, CH-1700 Fribourg, Switzerland

[2] Univ Lausanne Hosp, Dept Neurosurg, CH-1011 Lausanne, Switzerland

来源：

EXPERIMENTAL NEUROLOGY | 2005年 / 196卷 / 01期

关键词：

monkey; cell autotransplantation; brain repair;

D O I：

10.1016/j.expneurol.2005.04.005

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

If successful, autologous brain cell transplantation is an attractive approach to repair lesions and restore function of the central nervous 14 system. We demonstrate that monkey adult brain cells obtained from cortical biopsy and kept in culture for 4 weeks exhibit neural progenitor characteristics. After reimplantation into a lesion area of the donor cerebral cortex, these cells can successfully survive and acquire neuronal characteristics over time. These results open new perspectives in the field of brain repair and may lead to future clinical applications. (c) 2005 Elsevier Inc. All rights reserved.

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收藏

页码：195 / 198

页数：4

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