The acidocalcisome

被引：128

作者：

Docampo, R ^{[1
]}

Moreno, SNJ ^{[1
]}

机构：

[1] Univ Illinois, Coll Vet Med, Dept Pathobiol, Mol Parasitol Lab, Urbana, IL 61802 USA

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2001年 / 114卷 / 02期

关键词：

acidocalcisome; calcium; intracellular parasites; Leishmania; malaria; Toxoplasma gondii; Trypanosoma brucei; Trypanosoma cruzi; volutin granule;

D O I：

10.1016/S0166-6851(01)00246-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The acidocalcisome is an electron-dense acidic organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations. Its limiting membrane possesses a number of pumps and exchangers for the uptake and release of these elements. The acidocalcisome does not belong to the endocytic pathway and may represent a branch of the secretory pathway in trypanosomatids and apicomplexan parasites. The acidocalcisome is possibly involved in polyphosphate and cation storage and in adaptation of these microoganisms to environmental stress. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：151 / 159

页数：9

共 73 条

[1] LEISHMANIA-AMAZONENSIS - ACIDIC ORGANELLES IN AMASTIGOTES
ANTOINE, JC
JOUANNE, C
RYTER, A
BENICHOU, JC
[J]. EXPERIMENTAL PARASITOLOGY, 1988, 67 (02) : 287 - 300
[2] Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi
Benchimol, M
de Souza, W
Vanderheyden, N
Zhong, L
Lu, HG
Moreno, SNJ
Docampo, R
[J]. BIOCHEMICAL JOURNAL, 1998, 332 : 695 - 702
[3] Functional and molecular characterization of a glycosomal PPi-dependent enzyme in trypanosomatids:: Pyruvate, phosphate dikinase
Bringaud, F
Baltz, D
Baltz, T
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (14) : 7963 - 7968
[4] G-PROTEIN REGULATION OF THE NA+/H+ ANTIPORTER IN XENOPUS-LAEVIS OOCYTES - INVOLVEMENT OF PROTEIN-KINASE-A AND PROTEIN-KINASE-C
BUSCH, S
WIELAND, T
ESCHE, H
JAKOBS, KH
SIFFERT, W
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (30) : 17898 - 17901
[5] IN-SITU P-31 NUCLEAR-MAGNETIC-RESONANCE FOR OBSERVATION OF POLYPHOSPHATE AND CATABOLITE RESPONSES OF CHEMOSTAT-CULTIVATED SACCHAROMYCES-CEREVISIAE AFTER ALKALINIZATION
CASTRO, CD
MEEHAN, AJ
KORETSKY, AP
DOMACH, MM
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1995, 61 (12) : 4448 - 4453
[6] NMR-observed phosphate trafficking and polyphosphate dynamics in wild-type and vph1-1 mutant Saccharomyces cerevisiae in response to stresses
Castrol, CD
Koretsky, AP
Domach, MM
[J]. BIOTECHNOLOGY PROGRESS, 1999, 15 (01) : 65 - 73
[7] Chagas C., 1909, Memorias do Instituto Oswaldo Cruz, V1
[8] Chapman A G, 1977, Adv Microb Physiol, V15, P253, DOI 10.1016/S0065-2911(08)60318-5
[9] ROLE OF ACIDIC COMPARTMENTS IN TRYPANOSOMA-BRUCEI, WITH SPECIAL REFERENCE TO LOW-DENSITY-LIPOPROTEIN PROCESSING
COPPENS, I
BAUDHUIN, P
OPPERDOES, FR
COURTOY, PJ
[J]. MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1993, 58 (02) : 223 - 232
[10] CALCINEURIN-DEPENDENT GROWTH-CONTROL IN SACCHAROMYCES-CEREVISIAE MUTANTS LACKING PMC1, A HOMOLOG OF PLASMA-MEMBRANE CA2+ ATPASES
CUNNINGHAM, KW
FINK, GR
[J]. JOURNAL OF CELL BIOLOGY, 1994, 124 (03) : 351 - 363

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