Analysis of pesticide residues in fruit and vegetables with ethyl acetate extraction using gas and liquid chromatography with tandem mass spectrometric detection

被引:107
作者
Pihlstrom, Tuija
Blomkvist, Gun
Friman, Paula
Pagard, Ulla
Osterdahl, Bengt-Goeran
机构
[1] Natl Food Adm Toxicol Lab, Dept Res & Dev, S-75126 Uppsala, Sweden
[2] Lantmannen Analycen AB, SE-531 Lidkoping, Sweden
关键词
pesticides; multiresidue analysis; GC-MS/MS and LC-MS/MS; fruit and vegetables;
D O I
10.1007/s00216-007-1425-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A multiresidue method based on extraction with ethyl acetate has been used at the Swedish National Food Administration since 1989 to monitor pesticide residues in fruit and vegetables. The method has been continuously adjusted, resulting in simple and quick analyses of pesticide residues. To recover basic pesticides, the addition of an alkali is necessary. The addition of sodium hydrogen carbonate has been shown to recover all pesticides effectively without any degradation. The liquid chromatography (LC) with tandem mass spectrometry (MS/MS) technique has made it possible to analyse more polar pesticides and to replace many single methods. The latest development in the multiresidue method, comprising the use of gas chromatography (GC) with MS/MS, has further improved the analysis by replacing the conventional GC detectors. The need for cleanup has been reduced or eliminated entirely. Consequently, the method has been simplified in a way that makes it possible to recover all included analytes in many different matrices in one single extraction and to detect them either with GC-MS/MS or with LC-MS/MS.
引用
收藏
页码:1773 / 1789
页数:17
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