Mild and Selective H/D Exchange at the β Position of Aromatic α-Olefins by N-Heterocyclic Carbene-Hydride-Rhodium Catalysts

被引：65

作者：

Di Giuseppe, Andrea ^{[1
,2
]}

Castarlenas, Ricardo ^{[1
]}

Perez-Torrente, Jesus J. ^{[1
]}

Lahoz, Fernando J. ^{[1
]}

Polo, Victor ^{[3
]}

Oro, Luis A. ^{[1
]}

机构：

[1] Univ Zaragoza, Inst Univ Catalisis Homogenea, Inst Ciencia Mat Aragon, CSIC, E-50009 Zaragoza, Spain

[2] Univ Aquila, Dipartimento Chim Ingn Chim & Mat, I-67100 Coppito, AQ, Italy

[3] Univ Zaragoza, Dept Quim Fis, E-50009 Zaragoza, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2011年 / 50卷 / 17期

关键词：

H/D exchange; hydride ligands; N-heterocyclic carbene; rhodium; steric induction; C-H ACTIVATION; IRIDIUM(I) COMPLEXES; DEUTERIUM-OXIDE; LIGANDS; PALLADIUM; BOND; ISOMERIZATION; HYDROCARBONS; DEUTERATION; OXIDATION;

D O I：

10.1002/anie.201007238

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pacman bites selectively! Stable rhodium(III)-N-heterocyclic carbene-hydride complexes (Pacman-like catalysts) are highly active and selective catalysts for H/D exchange at the β position of aromatic α-olefins (see picture). The interplay between bulky N-heterocyclic carbene and quinolinate ligands determines the size of the steric window responsible for this selectivity. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：3938 / 3942

页数：5

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