Synthesis of sphingosine relatives .19. Synthesis of penaresidin A and B, azetidine alkaloids with actomyosin ATPase-activating properties

被引：53

作者：

Takikawa, H

Maeda, T

Seki, M

Koshino, H

Mori, K

机构：

[1] SCI UNIV TOKYO,DEPT CHEM,SHINJUKU KU,TOKYO 162,JAPAN

[2] INST PHYS & CHEM RES,WAKO,SAITAMA 35101,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1997年 / 02期

关键词：

D O I：

10.1039/a604276g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three stereoisomers of penaresidin A 1 and two stereoisomers of penaresidin B 2' (Scheme 5), azetidine alkaloids isolated from the Okinawan marine sponge Penares sp., have been synthesized. In the course of our synthetic study, the correct structure of penaresidin B has been shown to be not 2 but 2'. Natural penaresidin A is either (2S,3R,4S,15S,16S)- or (2S,3R,4S,15R,16R)-1 and natural penaresidin B is either (2S,3R,4S,15S)- or (2S,3R,4S,15R)-2'.

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页码：97 / 111

页数：15

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