Nucleotide sequence of genome segment 5 from Bombyx mori cypovirus 1

被引：40

作者：

Hagiwara, K

Kobayashi, J

Tomita, M

Yoshimura, T

机构：

[1] Mie Univ, Fac Engn, Dept Chem Mat, Mie, Japan

[2] Kyoto Inst Technol, Venture Lab, Kyoto 606, Japan

来源：

ARCHIVES OF VIROLOGY | 2001年 / 146卷 / 01期

关键词：

D O I：

10.1007/s007050170202

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The complete nucleotide sequences of the double-stranded RNA genome segments 5 (S5) from Bombyx mori cypovirus 1 (BmCPV-1) strains I and H were determined. The segments consisted of 2,852 nucleotides encoding putative proteins of 881 amino acids with molecular masses of approximately 101 kDa (p 101). A homology search showed that p101 has high similarity (93%) to foot-and-mouth disease virus (FMDV) 2A protease (2A(pro)) at amino acid position 219 to 235. These findings suggest the possibility that p101 encoded by BmCPV-1 S5 might be cleaved into two non-structural proteins by post-translational autocleavage involving a 2A(pro)-like protease.

引用

页码：181 / 187

页数：7