Fluorescence probes for thiol-containing amino acids and peptides in aqueous solution

被引：84

作者：

Fu, YY

Li, HX ^{[1
]}

Hu, WP

Zhu, DB

机构：

[1] Chinese Acad Sci, Inst Chem, Organ Solid Lab, Beijing 100080, Peoples R China

[2] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 25期

关键词：

D O I：

10.1039/b503772g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new fluorescence probe is described using the ''chemosensing ensemble'' method. The probe shows high selectivity and sensitivity for thiol-containing amino acids and peptides, and can detect cysteine and homocysteine from healthy to abnormal levels under physiologically-relevant conditions.

引用

收藏

页码：3189 / 3191

页数：3

相关论文

共 17 条

[1] A trinuclear heterobimetallic Ru(II)/Pt(II) complex as a chemodosimeter selective for sulfhydryl-containing amino acids and peptides [J].

Chow, CF ;

Chiu, BKW ;

Lam, MHW ;

Wong, WY .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (26) :7802-7803

[2]

Fabbrizzi L, 2001, ANGEW CHEM INT EDIT, V40, P3066, DOI 10.1002/1521-3773(20010817)40:16<3066::AID-ANIE3066>3.0.CO

[3]

2-0

[4]

Fabbrizzi L, 2002, ANGEW CHEM INT EDIT, V41, P3811, DOI 10.1002/1521-3773(20021018)41:20<3811::AID-ANIE3811>3.0.CO

[5]

2-W

[6] Designing the selectivity of the fluorescent detection of amino acids:: A chemosensing ensemble for histidine [J].

Hortalá, MA ;

Fabbrizzi, L ;

Marcotte, N ;

Stomeo, F ;

Taglietti, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (01) :20-21

[7] A cyclometalated palladium-azo complex as a differential chromogenic probe for amino acids in aqueous solution [J].

Li, SH ;

Yu, CW ;

Xu, JG .

CHEMICAL COMMUNICATIONS, 2005, (04) :450-452

[8] Analytical determination of homocysteine: a review [J].

Nekrassova, O ;

Lawrence, NS ;

Compton, RG .

TALANTA, 2003, 60 (06) :1085-1095

[9] Homocysteine and cardiovascular disease [J].

Refsum, H ;

Ueland, PM ;

Nygård, O ;

Vollset, SE .

ANNUAL REVIEW OF MEDICINE, 1998, 49 :31-62

[10] Squaraines as fluoro-chromogenic probes for thiol-containing compounds and their application to the detection of biorelevant thiols [J].

Ros-Lis, JV ;

García, B ;

Jiménez, D ;

Martínez-Máñez, R ;

Sancenon, F ;

Soto, J ;

Gonzalvo, F ;

Valldecabres, MC .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (13) :4064-4065