A trinuclear heterobimetallic Ru(II)/Pt(II) complex as a chemodosimeter selective for sulfhydryl-containing amino acids and peptides

被引：120

作者：

Chow, CF

Chiu, BKW

Lam, MHW

Wong, WY

机构：

[1] City Univ Hong Kong, Dept Biol Chem, Hong Kong, Peoples R China

[2] Hong Kong Baptist Univ, Dept Chem, Kowloon, Hong Kong, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 26期

关键词：

D O I：

10.1021/ja034891x

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A trinuclear heterobimetallic Ru(II)/Pt(II) complex, cis-{Ru(phen)2[CN-Pt(DMSO)Cl2]2} (phen = 1,10-phenanthroline), is able to function as a switch-on" luminescent chemodosimeter for sulfhydryl-containing amino acids and peptides via specific binding of the amino acids/peptides with the Pt(II) centers and the subsequent cleavage of the Ru(II)-Pt(II) cyano-bridge. Copyright © 2003 American Chemical Society."

引用

页码：7802 / 7803

页数：2

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