Minor diterpenoid glycosides from the leaves of Stevia rebaudiana

被引：42

作者：

Chaturvedula, Venkata Sai Prakash ^{[1
]}

Clos, John F. ^{[1
]}

Rhea, Joshua ^{[2
]}

Milanowski, Dennis ^{[2
]}

Mocek, Ulla ^{[2
]}

DuBois, Grant E. ^{[1
]}

Prakash, Indra ^{[1
]}

机构：

[1] Coca Cola Co, Res & Technol, Atlanta, GA 30313 USA

[2] Bothell Res Ctr, AMRI, Bothell, WA 98021 USA

来源：

PHYTOCHEMISTRY LETTERS | 2011年 / 4卷 / 03期

关键词：

Stevia rebaudiana; Compositae; Asteraceae; Diterpenoid glycosides; NMR; MS; C-13; NMR-SPECTROSCOPY; OLEANANE SAPONINS; GLUCOSIDES; CHEMISTRY;

D O I：

10.1016/j.phytol.2011.01.002

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

From the commercial extract of the leaves of Stevia rebaudiana, three new diterpenoid glycosides were isolated besides eight known steviol glycosides including stevioside, rebaudiosides A-F and dulcoside A. The structures of the three compounds were identified as 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) oxy]-kaur-16-en-18-oic acid-(6-O-beta-D-xylopyranosyl-beta-D-glucopyranosyl) ester (1), 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) oxy]-17-hydroxy-kaur-15-en-18-oic acid beta-D-glucopyranosyl ester (2), and 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) oxy]-17-oxo-kaur-15-en-18-oic acid beta-D-glucopyranosyl ester (3) on the basis of extensive NMR and MS spectral studies. Another known diterpenoid glycoside, 13-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl) oxy]-kaur-15-en-18-oic acid beta-D-glucopyranosyl ester (4) was also isolated and its complete NMR spectral assignments were made on the basis of COSY, HSQC and HMBC spectral data. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：209 / 212

页数：4

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