HIV postexposure prophylaxis in the 21st century

被引:13
作者
Henderson, DK [1 ]
机构
[1] NIH, Warren G Magnuson Clin Ctr, Bethesda, MD 20892 USA
关键词
D O I
10.3201/eid0702.010221
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The administration of postexposure prophylaxis has become the standard of care for occupational exposures to HIV. We have learned a great deal about the safety and potential efficacy of these agents, as well as the optimal management of health-care workers occupationally exposed to HIV. This article describes the current state of knowledge in this field, identifies substantive questions to be answered, and summarizes basic principles of postexposure management.
引用
收藏
页码:254 / 258
页数:5
相关论文
共 44 条
[1]  
[Anonymous], 1998, MMWR Recomm Rep, V47, P1
[2]   Postexposure prophylaxis for occupational exposure to HIV [J].
Bangsberg, D ;
Goldschmidt, RH .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (17) :1623-1624
[3]   Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population [J].
Bangsberg, DR ;
Hecht, FM ;
Charlebois, ED ;
Zolopa, AR ;
Holodniy, M ;
Sheiner, L ;
Bamberger, JD ;
Chesney, MA ;
Moss, A .
AIDS, 2000, 14 (04) :357-366
[4]   TEMPORAL ASSOCIATION BETWEEN IMPLEMENTATION OF UNIVERSAL PRECAUTIONS AND A SUSTAINED, PROGRESSIVE DECREASE IN PERCUTANEOUS EXPOSURES TO BLOOD [J].
BEEKMANN, SE ;
VLAHOV, D ;
KOZIOL, DE ;
MCSHALLEY, ED ;
SCHMITT, JM ;
HENDERSON, DK .
CLINICAL INFECTIOUS DISEASES, 1994, 18 (04) :562-569
[5]  
BELTRAMI EM, 2000, P 4 DEC C NOS INF AT
[6]   Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues [J].
Blanche, S ;
Tardieu, M ;
Rustin, P ;
Slama, A ;
Barret, B ;
Firtion, G ;
Ciraru-Vigneron, N ;
Lacroix, C ;
Rouzioux, C ;
Mandelbrot, L ;
Desguerre, I ;
Rötig, A ;
Mayaux, MJ ;
Delfraissy, JF .
LANCET, 1999, 354 (9184) :1084-1089
[7]  
BLANCHE S, 1999, P 6 ANN C RETR OPP I
[8]   Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005 [J].
Bottiger, D ;
Johansson, NG ;
Samuelsson, B ;
Zhang, H ;
Putkonen, P ;
Vrang, L ;
Oberg, B .
AIDS, 1997, 11 (02) :157-162
[9]  
BULTERYS M, 1999, GLOBAL STRATEGIES PR
[10]   A case-control study of HIV seroconversion in health care workers after percutaneous exposure [J].
Cardo, DM ;
Culver, DH ;
Ciesielski, CA ;
Srivastava, PU ;
Marcus, R ;
Abiteboul, D ;
Heptonstall, J ;
Ippolito, G ;
Lot, F ;
McKibben, P ;
Bell, DM .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (21) :1485-1490