Convenient transformation of optically active nitroalkanes into chiral aldoximes and nitriles

被引：132

作者：

Czekelius, C ^{[1
]}

Carreira, EM ^{[1
]}

机构：

[1] ETH Honggerberg, Organ Chem Lab, CH-8093 Zurich, Switzerland

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 04期

关键词：

chirality; nitro compounds; oximes; reduction; synthetic methods;

D O I：

10.1002/anie.200461879

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An environmentally friendly reaction that excludes the potential contamination of the products by metal impurities is reported. In this reaction, optically active aldoximes and nitriles are prepared from chiral nitroalkanes (see scheme). The methodology described expands the possibilities available for the conversion of nitroalkanes into valuable targets.

引用

页码：612 / 615

页数：4

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