Inherited platelet disorders

被引：19

作者：

Hayward, CPM

机构：

[1] McMaster Univ, Hamilton, ON L8N 3Z5, Canada

[2] Hamilton Reg Lab Med Program, Hamilton, ON L8N 3Z5, Canada

来源：

CURRENT OPINION IN HEMATOLOGY | 2003年 / 10卷 / 05期

关键词：

congenital platelet disorders; inherited bleeding disorders; thrombocytopenia; platelet function; platelet aggregation;

D O I：

10.1097/00062752-200309000-00007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Inherited platelet disorders are important causes of bleeding that can quantitatively and qualitatively alter platelets, impairing their function. The purpose of this review is to summarize current knowledge on the different types of inherited platelet disorders, their clinical and laboratory features, molecular genetic causes, and the therapies used in clinical practice to manage these conditions. (C) 2003 Lippincott Williams Wilkins.

引用

收藏

页码：362 / 368

页数：7

相关论文

共 59 条

[21] Hermansky-Pudlak Syndrome Type 1: Gene Organization, Novel Mutations, and Clinical-Molecular Review of Non-Puerto Rican Cases [J].

Hermos, Christina R. ;

Huizing, Marjan ;

Kaiser-Kupfer, Muriel I. ;

Gahl, William A. .

HUMAN MUTATION, 2002, 20 (06) :482

[22]

Higuchi W, 1999, THROMB HAEMOSTASIS, V82, P1528

[23] Identification of the platelet ADP receptor targeted by antithrombotic drugs [J].

Hollopeter, G ;

Jantzen, HM ;

Vincent, D ;

Li, G ;

England, L ;

Ramakrishnan, V ;

Yang, RB ;

Nurden, P ;

Nurden, A ;

Julius, D ;

Conley, PB .

NATURE, 2001, 409 (6817) :202-207

[24]

Huizing M, 2002, Curr Mol Med, V2, P451, DOI 10.2174/1566524023362357

[25] Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia [J].

Ihara, K ;

Ishii, E ;

Eguchi, M ;

Takada, H ;

Suminoe, A ;

Good, RA ;

Hara, T .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (06) :3132-3136

[26] DDAVP nasal spray for treatment of menorrhagia in women with inherited bleeding disorders: a randomized placebo-controlled crossover study [J].

Kadir, RA ;

Lee, CA ;

Sabin, CA ;

Pollard, D ;

Economides, DL .

HAEMOPHILIA, 2002, 8 (06) :787-793

[27] Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinase-type plasminogen activator [J].

Kahr, WHA ;

Zheng, SL ;

Sheth, PM ;

Pai, M ;

Cowie, A ;

Bouchard, M ;

Podor, TJ ;

Rivard, GE ;

Hayward, CPM .

BLOOD, 2001, 98 (02) :257-265

[28] Identification of six novel MYH9 mutations and genotype-phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions [J].

Kunishima, S ;

Matsushita, T ;

Kojima, T ;

Amemiya, N ;

Choi, YM ;

Hosaka, N ;

Inoue, M ;

Jung, Y ;

Mamiya, S ;

Matsumoto, K ;

Miyajima, Y ;

Zhang, GS ;

Ruan, CG ;

Saito, K ;

Song, KS ;

Yoon, HJ ;

Kamiya, T ;

Saito, H .

JOURNAL OF HUMAN GENETICS, 2001, 46 (12) :722-729

[29]

LETHABY A, 2003, COCHRANE LIB, P1

[30] Protein A Sepharose immunoadsorption can restore the efficacy of platelet concentrates in patients with Glanzmann's thrombasthenia and anti-glycoprotein IIb-IIIa antibodies [J].

Martin, I ;

Kriaa, F ;

Proulle, VR ;

Guillet, B ;

Kaplan, C ;

d'Oiron, R ;

Debré, M ;

Fressinaud, E ;

Laurian, Y ;

Tchernia, G ;

Charpentier, B ;

Lambert, T ;

Dreyfus, M .

BRITISH JOURNAL OF HAEMATOLOGY, 2002, 119 (04) :991-997

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