The 7-oxabicyclo[2.2.1]heptane system as a valuable starting material for the synthesis of modified a ring vitamin D3 analogues

被引：17

作者：

Arjona, O ^{[1
]}

Iradier, F

Plumet, J

Martínez-Alcázar, MP

Hernández-Cano, F

Fonseca, I

机构：

[1] Univ Complutense, Fac Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

[2] Univ San Pablo, Fac Ciencias Expt & Tecn, Dept Ciencias Basicas, Madrid, Spain

[3] CSIC, Inst Rocasolano, Dept Cristalog, E-28006 Madrid, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(98)01414-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A totally stereoselective synthesis of an analogue of the A ring fragment of vitamin D-3 has been achieved in optically pure form starting from a 7-oxanorbornenic disulfone. The key step is the alkylative cleavage of the oxygen bridge to produce a highly oxygenated cyclohexenyl sulfone. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：6741 / 6744

页数：4

共 31 条

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