Gastric cancer

被引：103

作者：

Catalano, V ^{[1
]}

Labianca, R

Beretta, GD

Gatta, G

de Braud, F

Van Cutsem, E

机构：

[1] Azienda Osped Osped San Salvatore, Pesaro, Italy

[2] Osped Riuniti Bergamo, I-24100 Bergamo, Italy

[3] Ist Nazl Studio & Cura Tumori, Milan, Italy

[4] START Project, Milan, Italy

[5] Ist Europeo Oncol, Milan, Italy

[6] Univ Hosp Gasthuisberg, B-3000 Louvain, Belgium

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2005年 / 54卷 / 03期

关键词：

D O I：

10.1016/j.critrevonc.2005.01.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Gastric cancer is one of the most common cancers and one of the most frequent causes of cancer-related deaths. The incidence, diagnostic studies, and therapeutic options have undergone important changes in the last decades, but the prognosis for gastric cancer patients remains poor, especially in more advanced stages. Surgery is the mainstay of treatment of this disease, even if it is associated with a high rate of locoregional and distant recurrence. There is ongoing debate regarding the role of adjuvant treatment In advanced disease, palliation of symptoms, rather than cure, is the primary goal of patient management. Several combination therapies have been developed and have been examined in phase III trials; however, in most cases, they have failed to demonstrate a survival advantage over the reference arm. This review summarizes the most important recommendations for the management of patients with gastric cancer. (c) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：209 / 241

页数：33

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