Tandem Cyclization-Michael Reaction by Combination of Metal- and Organocatalysis

被引：18

作者：

Aleman, Jose ^{[1
]}

del Solar, Virginia ^{[2
]}

Martin-Santos, Cecilia ^{[2
]}

Cubo, Leticia ^{[2
]}

Navarro Ranningers, Carmen ^{[2
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ C1, E-28049 Madrid, Spain

[2] Univ Autonoma Madrid, Dept Quim Inorgan C7, Fac Ciencias, E-28049 Madrid, Spain

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2011年 / 76卷 / 17期

关键词：

BRONSTED ACID; ASYMMETRIC-SYNTHESIS; ALKYNYLATION; AMINATION; CATALYSIS; ETHERS;

D O I：

10.1021/jo2013077

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The use of a catalytic amount of platinum complexes (1 mol %) was found to be compatible with different organocatalysts (DABCO or the Jorgensen-Hayashi catalyst) that were used in the functionalization of various activated methylenes. By this method, a series of lactones with C-3 quaternary centers and substitution at C-5 were prepared.

引用

页码：7287 / 7293

页数：7

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