Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media

被引：40

作者：

Aleman, Jose ^{[1
]}

del Solar, Virginia ^{[2
]}

Navarro-Ranninger, Carmen ^{[2
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ C1, E-28049 Madrid, Spain

[2] Univ Autonoma Madrid, Dept Quim Inorgan C8, E-28049 Madrid, Spain

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 03期

关键词：

ACIDS; ALKYNES; ANALOGS; DESIGN; DRUGS;

D O I：

10.1039/b917758b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient cyclization of alkyne-acids to enol-lactones catalyzed by anticancer platinum(II) and platinum(IV) compounds is described. These compounds are not only DNA-binding complexes; they can also catalyze reactions in solvents such as acetone, methanol, water or blood plasma.

引用

页码：454 / 456

页数：3

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