Neuronal basis of sequential foraging decisions in a patchy environment

被引:310
作者
Hayden, Benjamin Y. [1 ,2 ]
Pearson, John M. [1 ,2 ]
Platt, Michael L. [1 ,2 ,3 ]
机构
[1] Duke Univ, Sch Med, Dept Neurobiol, Durham, NC 27710 USA
[2] Duke Univ, Ctr Cognit Neurosci, Durham, NC USA
[3] Duke Univ, Dept Evolutionary Anthropol, Durham, NC USA
基金
美国国家卫生研究院;
关键词
ANTERIOR CINGULATE CORTEX; REWARD SIGNALS; PREDICTION ERRORS; UNCERTAINTY; DOPAMINE; STRATEGY; CHOICE; BRAIN; DELAY; AREA;
D O I
10.1038/nn.2856
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Deciding when to leave a depleting resource to exploit another is a fundamental problem for all decision makers. The neuronal mechanisms mediating patch-leaving decisions remain unknown. We found that neurons in primate (Macaca mulatta) dorsal anterior cingulate cortex, an area that is linked to reward monitoring and executive control, encode a decision variable signaling the relative value of leaving a depleting resource for a new one. Neurons fired during each sequential decision to stay in a patch and, for each travel time, these responses reached a fixed threshold for patch-leaving. Longer travel times reduced the gain of neural responses for choosing to stay in a patch and increased the firing rate threshold mandating patch-leaving. These modulations more closely matched behavioral decisions than any single task variable. These findings portend an understanding of the neural basis of foraging decisions and endorse the unification of theoretical and experimental work in ecology and neuroscience.
引用
收藏
页码:933 / U165
页数:9
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