Dietary Restriction: Standing Up for Sirtuins

被引：56

作者：

Baur, Joseph A. ^{[2
]}

Chen, Danica ^{[3
]}

Chini, Eduardo N. ^{[4
]}

Chua, Katrin ^{[5
]}

Cohen, Haim Y. ^{[6
]}

De Cabo, Rafael ^{[7
]}

Deng, Chuxia ^{[8
]}

Dimmeler, Stefanie ^{[9
]}

Gius, David ^{[10
]}

Guarente, Leonard P. ^{[1
]}

Helfand, Stephen L. ^{[11
]}

Imai, Shin-Ichiro ^{[12
]}

Itoh, Hiroshi ^{[13
]}

Kadowaki, Takashi ^{[14
]}

Koya, Daisuke ^{[15
]}

Leeuwenburgh, Christiaan ^{[16
]}

Mcburney, Michael ^{[17
]}

Nabeshima, Yo-Ichi ^{[18
]}

Neri, Christian ^{[19
]}

Oberdoerffer, Philipp ^{[20
]}

Pestell, Richard G. ^{[21
]}

Rogina, Blanka ^{[22
]}

Sadoshima, Junichi ^{[23
]}

Sartorelli, Vittorio ^{[24
]}

Serrano, Manuel ^{[25
]}

Sinclair, David A. ^{[26
]}

Steegborn, Clemens ^{[27
]}

Tatar, Marc ^{[28
]}

Tissenbaum, Heidi A. ^{[29
]}

Tong, Qiang ^{[30
]}

Tsubota, Kazuo ^{[31
]}

Vaquero, Alejandro ^{[32
,33
]}

Verdin, Eric ^{[34
]}

机构：

[1] MIT, Dept Biol, Cambridge, MA 02139 USA

[2] Univ Penn, Sch Med, Dept Physiol, Philadelphia, PA 19104 USA

[3] Univ Calif Berkeley, Dept Nutr Sci & Toxicol, Berkeley, CA 94720 USA

[4] St Marys Hosp, Mayo Clin, Rochester, MN 55905 USA

[5] Stanford Univ, Dept Med, Palo Alto, CA 94305 USA

[6] Bar Ilan Univ, Mina & Everard Goodman Fac Life Sci, IL-52900 Ramat Gan, Israel

[7] NIA, Lab Expt Gerontol, NIH, Baltimore, MD 21224 USA

[8] NIDDKD, Genet Dev & Dis Branch, NIH, Bethesda, MD 20892 USA

[9] Goethe Univ Frankfurt, Dept Internal Med 3, D-60325 Frankfurt, Germany

[10] Vanderbilt Univ, Med Ctr, Dept Radiat Oncol & Pediat, Nashville, TN 37232 USA

[11] Brown Univ, Dept Mol Biol Cell Biol & Biochem, Providence, RI 02912 USA

[12] Washington Univ, Sch Med, Dept Dev Biol, St Louis, MO 63110 USA

[13] Keio Univ, Sch Med, Div Endocrinol Metab & Nephrol, Tokyo, Japan

[14] Univ Tokyo, Dept Diabet & Metab Dis, Tokyo 1608582, Japan

[15] Kanazawa Med Univ, Uchinada, Ishikawa 9200293, Japan

[16] Univ Florida, Dept Aging & Geriatr, Gainesville, FL 32611 USA

[17] Ottawa Hlth Res Inst, Dept Med & Biochem, Ottawa, ON K1H 8L6, Canada

[18] Inst Biomed Res & Innovat Fdn Biomed Res & Innova, Chuo Ku, Kobe, Hyogo 6500047, Japan

[19] INSERM, U894, Lab Neuronal Cell Biol & Pathol, F-75014 Paris, France

[20] NCI, Mouse Canc Genet Program, NIH, Frederick, MD 21702 USA

[21] Thomas Jefferson Univ, Kimmel Canc Ctr, Dept Canc Biol & Med Oncol, Philadelphia, PA 19107 USA

[22] Univ Connecticut, Ctr Hlth, Dept Genet & Dev Biol, Farmington, CT 06030 USA

[23] Univ Med & Dent New Jersey, Cardiovasc Res Inst, Newark, NJ 07103 USA

[24] NIAMSD, Lab Muscle Stem Cells & Gene Regulat, NIH, Bethesda, MD 20892 USA

[25] Spanish Natl Canc Res Ctr CNIO, Madrid, Spain

[26] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA

[27] Univ Bayreuth, Dept Biochem, D-95440 Bayreuth, Germany

[28] Brown Univ, Dept Ecol & Evolut Biol, Providence, RI 02912 USA

[29] Univ Massachusetts, Sch Med, Program Gene Funct & Express, Worcester, MA 01605 USA

[30] Baylor Coll Med, Houston, TX 77030 USA

[31] Keio Univ, Sch Med, Dept Ophthalmol, Tokyo, Japan

[32] ICREA, PEBC, Barcelona 08907, Spain

[33] IDIBELL, Barcelona 08907, Spain

[34] Univ Calif San Francisco, Gladstone Inst Virol & Immunol, San Francisco, CA 94158 USA

来源：

SCIENCE | 2010年 / 329卷 / 5995期

关键词：

CALORIC RESTRICTION; LIFE-SPAN; DROSOPHILA; DISEASE; SIRT1;

D O I：

10.1126/science.329.5995.1012

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：1012 / 1013

页数：2

共 9 条

[1] SirT1 Regulates Energy Metabolism and Response to Caloric Restriction in Mice [J].

Boily, Gino ;

Seifert, Erin L. ;

Bevilacqua, Lisa ;

He, Xiao Hong ;

Sabourin, Guillaume ;

Estey, Carmen ;

Moffat, Cynthia ;

Crawford, Sean ;

Saliba, Sarah ;

Jardine, Karen ;

Xuan, Jian ;

Evans, Meredith ;

Harper, Mary-Ellen ;

McBurney, Michael W. .

PLOS ONE, 2008, 3 (03)

[2] Calorie restriction increases muscle mitochondrial biogenesis in healthy humans [J].

Civitarese, Anthony E. ;

Carling, Stacy ;

Heilbronn, Leonie K. ;

Hulver, Mathew H. ;

Ukropcova, Barbara ;

Deutsch, Walter A. ;

Smith, Steven R. ;

Ravussin, Eric .

PLOS MEDICINE, 2007, 4 (03) :485-494

[3] Recent progress in the biology and physiology of sirtuins [J].

Finkel, Toren ;

Deng, Chu-Xia ;

Mostoslavsky, Raul .

NATURE, 2009, 460 (7255) :587-591

[4] Drosophila, germ-line modulation of insulin signaling and lifespan [J].

Flatt, Thomas ;

Min, Kyung-Jin ;

D'Alterio, Cecilia ;

Villa-Cuesta, Eugenia ;

Cumbers, John ;

Lehmann, Ruth ;

Jones, D. Leanne ;

Tatar, Marc .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (17) :6368-6373

[5] Mammalian Sirtuins: Biological Insights and Disease Relevance [J].

Haigis, Marcia C. ;

Sinclair, David A. .

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, 2010, 5 :253-295

[6] Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases [J].

Imai, Shin-ichiro ;

Guarente, Leonard .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2010, 31 (05) :212-220

[7] Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α [J].

Lagouge, Marie ;

Argmann, Carmen ;

Gerhart-Hines, Zachary ;

Meziane, Hamid ;

Lerin, Carles ;

Daussin, Frederic ;

Messadeq, Nadia ;

Milne, Jill ;

Lambert, Philip ;

Elliott, Peter ;

Geny, Bernard ;

Laakso, Markku ;

Puigserver, Pere ;

Auwerx, Johan .

CELL, 2006, 127 (06) :1109-1122

[8] The genetics of caloric restriction in Caenorhabditis elegans [J].

Lakowski, B ;

Hekimi, S .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (22) :13091-13096

[9] Drosophila lifespan control by dietary restriction independent of insulin-like signaling [J].

Min, Kyung-Jin ;

Yamamoto, Rochele ;

Buch, Susanne ;

Pankratz, Michael ;

Tatar, Marc .

AGING CELL, 2008, 7 (02) :199-206

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