Neutralising antibody responses in cattle and sheep following booster vaccination with two commercial inactivated bluetongue virus serotype 8 vaccines

被引：9

作者：

Bartram, David J. ^{[1
]}

Heasman, Lindsay ^{[2
]}

Batten, Carrie A. ^{[3
]}

Oura, Christopher A. L. ^{[3
]}

Plana-Duran, Joan ^{[4
]}

Yuen, Ho Ming ^{[5
]}

Wylie, Andrew D. M. ^{[1
]}

机构：

[1] Ft Dodge Anim Hlth, Southampton SO30 4QH, Hants, England

[2] Dawes Farm, Westpoint Vet Grp, Warnham RH12 3SH, W Sussex, England

[3] Inst Anim Hlth, Dept Arbovirol, Surrey GU24 ONF, England

[4] Ft Dodge Vet SA, Vall De Bianya Gerona 17813, Spain

[5] Univ Southampton, Southampton Gen Hosp, Sch Med, Southampton SO16 6YD, Hants, England

来源：

VETERINARY JOURNAL | 2011年 / 188卷 / 02期

关键词：

Bluetongue; Inactivated vaccine; Booster; Neutralising antibodies; EUROPE;

D O I：

10.1016/j.tvjl.2010.04.001

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Cattle and sheep that had received a primary course of vaccination with an inactivated bluetongue virus serotype 8 (BTV-8) vaccine were booster vaccinated 6 or 12 months later with the homologous vaccine or an alternative inactivated BTV-8 vaccine and neutralising antibody responses were determined. Antibody titres to the alternative vaccine were significantly higher than to the homologous vaccine (P = 0.013) in cattle. There was no significant difference between the antibody responses to alternative and homologous vaccines in sheep. These data indicate that cattle and sheep primed with one inactivated BTV-8 vaccine may be effectively boosted with an alternative commercial inactivated BTV-8 vaccine. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：193 / 196

页数：4

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