Discovery of O-GlcNAc transferase inhibitors

[1] HALTIWANGER RS, 1992, J BIOL CHEM, V267, P9005

[2] Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2003, 409 (02) : 287 - 297

[3] Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (37) : 11168 - 11169

[4] Identification of selective inhibitors for the glycosyltransferase via high-throughput murG screening [J]. CHEMISTRY & BIOLOGY, 2004, 11 (05): : 703 - 711

[5] Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 293 (01) : 207 - 212

[6] Regulation of a cytosolic and nuclear O-GlcNAc transferase -: Role of the tetratricopeptide repeats [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) : 32015 - 32022

[7] Functional expression of O-linked GlcNAc transferase -: Domain structure and substrate specificity [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (15) : 10983 - 10988

[8] Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors:: kinetics of cytosolic OGT accumulation and nuclear translocation [J]. ANALYTICAL BIOCHEMISTRY, 2003, 319 (02) : 304 - 313

[9] One-step synthesis of labeled sugar nucleotides for protein O-GlcNAc modification studies by chemical function analysis of an archaeal protein [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (03) : 836 - 837

[10] Identification of inhibitors for UDP-galactopyranose mutase [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (34) : 10532 - 10533

[1] HALTIWANGER RS, 1992, J BIOL CHEM, V267, P9005

[2] Mitochondrial and nucleocytoplasmic isoforms of O-linked GlcNAc transferase encoded by a single mammalian gene [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2003, 409 (02) : 287 - 297

[3] Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (37) : 11168 - 11169

[4] Identification of selective inhibitors for the glycosyltransferase via high-throughput murG screening [J]. CHEMISTRY & BIOLOGY, 2004, 11 (05): : 703 - 711

[5] Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 293 (01) : 207 - 212

[6] Regulation of a cytosolic and nuclear O-GlcNAc transferase -: Role of the tetratricopeptide repeats [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) : 32015 - 32022

[7] Functional expression of O-linked GlcNAc transferase -: Domain structure and substrate specificity [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (15) : 10983 - 10988

[8] Enhanced expression of uridine diphosphate-N-acetylglucosaminyl transferase (OGT) in a stable, tetracycline-inducible HeLa cell line using histone deacetylase inhibitors:: kinetics of cytosolic OGT accumulation and nuclear translocation [J]. ANALYTICAL BIOCHEMISTRY, 2003, 319 (02) : 304 - 313

[9] One-step synthesis of labeled sugar nucleotides for protein O-GlcNAc modification studies by chemical function analysis of an archaeal protein [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (03) : 836 - 837

[10] Identification of inhibitors for UDP-galactopyranose mutase [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (34) : 10532 - 10533