Structural insight into functional aspects of ribosomal RNA targeting

被引：19

作者：

Yonath, A ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biol Struct, IL-76100 Rehovot, Israel

[2] Max Planck Res Unit Ribosomal Struct, D-22603 Hamburg, Germany

来源：

CHEMBIOCHEM | 2003年 / 4卷 / 10期

关键词：

antibiotics; exit tunnel; peptide bond formation; ribosomes; RNA;

D O I：

10.1002/cbic.200300683

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：1008 / 1017

页数：10

共 57 条

[1] On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes - Delivered on 20 October 2002 at the 28th FEBS Meeting in Istanbul [J].

Agmon, I ;

Auerbach, T ;

Baram, D ;

Bartels, H ;

Bashan, A ;

Berisio, R ;

Fucini, P ;

Hansen, HAS ;

Harms, J ;

Kessler, M ;

Peretz, M ;

Schluenzen, F ;

Yonath, A ;

Zarivach, R .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 2003, 270 (12) :2543-2556

[2]

Auerbach Tamar, 2002, Current Drug Targets - Infectious Disorders, V2, P169, DOI 10.2174/1568005023342506

[3] The complete atomic structure of the large ribosomal subunit at 2.4 Å resolution [J].

Ban, N ;

Nissen, P ;

Hansen, J ;

Moore, PB ;

Steitz, TA .

SCIENCE, 2000, 289 (5481) :905-920

[4]

Berg J M, 2001, Science, V291, P203

[5] Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression [J].

Bashan, A ;

Agmon, I ;

Zarivach, R ;

Schluenzen, F ;

Harms, J ;

Berisio, R ;

Bartels, H ;

Franceschi, F ;

Auerbach, T ;

Hansen, HAS ;

Kossoy, E ;

Kessler, M ;

Yonath, A .

MOLECULAR CELL, 2003, 11 (01) :91-102

[6] A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition [J].

Bayfield, MA ;

Dahlberg, AE ;

Schulmeister, U ;

Dorner, S ;

Barta, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (18) :10096-10101

[7] Structural insight into the antibiotic action of telithromycin against resistant mutants [J].

Berisio, R ;

Harms, J ;

Schluenzen, F ;

Zarivach, R ;

Hansen, HAS ;

Fucini, P ;

Yonath, A .

JOURNAL OF BACTERIOLOGY, 2003, 185 (14) :4276-4279

[8] Structural insight into the role of the ribosomal tunnel in cellular regulation [J].

Berisio, R ;

Schluenzen, F ;

Harms, J ;

Bashan, A ;

Auerbach, T ;

Baram, D ;

Yonath, A .

NATURE STRUCTURAL BIOLOGY, 2003, 10 (05) :366-370

[9] L22 ribosomal protein and effect of its mutation on ribosome resistance to erythromycin [J].

Davydova, N ;

Streltsov, V ;

Wilce, M ;

Liljas, A ;

Garber, M .

JOURNAL OF MOLECULAR BIOLOGY, 2002, 322 (03) :635-644

[10] Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA [J].

Douthwaite, S ;

Hansen, LH ;

Mauvais, P .

MOLECULAR MICROBIOLOGY, 2000, 36 (01) :183-192

← 1 2 3 4 5 6 →