Lessons from the CYP3A4 promoter

被引：36

作者：

Schuetz, EG ^{[1
]}

机构：

[1] St Jude Childrens Res Hosp, Dept Pharmaceut Sci, Memphis, TN 38105 USA

来源：

MOLECULAR PHARMACOLOGY | 2004年 / 65卷 / 02期

关键词：

D O I：

10.1124/mol.65.2.279

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：279 / 281

页数：3

共 39 条

[1] SXR, a novel steroid and xenobiotic-sensing nuclear receptor [J].

Blumberg, B ;

Sabbagh, W ;

Juguilon, H ;

Bolado, J ;

van Meter, CM ;

Ono, ES ;

Evans, RM .

GENES & DEVELOPMENT, 1998, 12 (20) :3195-3205

[2] TRAPping enhancer function [J].

Bulger, M ;

Groudine, M .

NATURE GENETICS, 2002, 32 (04) :555-556

[3] Constitutive androstane receptor and pregnane X receptor gene expression in human liver: Interindividual variability and correlation with CYP2B6 mRNA levels [J].

Chang, TKH ;

Bandiera, SM ;

Chen, J .

DRUG METABOLISM AND DISPOSITION, 2003, 31 (01) :7-10

[4] Identification and functional characterization of eight CYP3A4 protein variants [J].

Eiselt, R ;

Domanski, TL ;

Zibat, A ;

Mueller, R ;

Presecan-Siedel, E ;

Hustert, E ;

Zanger, UM ;

Brockmoller, J ;

Klenk, HP ;

Meyer, UA ;

Khan, KK ;

He, YA ;

Halpert, JR ;

Wojnowski, L .

PHARMACOGENETICS, 2001, 11 (05) :447-458

[5] Association of CYP3A4 genotype with treatment-related leukemia [J].

Felix, CA ;

Walker, AH ;

Lange, BJ ;

Williams, TM ;

Winick, NJ ;

Cheung, NKV ;

Lovett, BD ;

Nowell, PC ;

Blair, IA ;

Rebbeck, TR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (22) :13176-13181

[6] The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons [J].

Finta, C ;

Zaphiropoulos, PG .

GENE, 2000, 260 (1-2) :13-23

[7] Genotype-phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women [J].

Floyd, MD ;

Gervasini, G ;

Masica, AL ;

Mayo, G ;

George, AL ;

Bhat, K ;

Kim, RB ;

Wilkinson, GR .

PHARMACOGENETICS, 2003, 13 (10) :595-606

[8] The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module [J].

Goodwin, B ;

Hodgson, E ;

Liddle, C .

MOLECULAR PHARMACOLOGY, 1999, 56 (06) :1329-1339

[9] Expression of the human CYP3A4 gene in the small intestine of transgenic mice:: In vitro metabolism and pharmacokinetics of midazolam [J].

Granvil, CP ;

Yu, AM ;

Elizondo, G ;

Akiyama, TE ;

Cheung, C ;

Feigenbaum, L ;

Krausz, KW ;

Gonzalez, FJ .

DRUG METABOLISM AND DISPOSITION, 2003, 31 (05) :548-558

[10] Globin gene switching in primates [J].

Johnson, RM ;

Gumucio, D ;

Goodman, M .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY, 2002, 133 (03) :877-883

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