TRAPping enhancer function

被引：8

作者：

Bulger, M ^{[1
]}

Groudine, M

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98125 USA

[2] Univ Washington, Sch Med, Dept Radiat Oncol, Seattle, WA 98195 USA

来源：

NATURE GENETICS | 2002年 / 32卷 / 04期

关键词：

D O I：

10.1038/ng1202-555

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Enhancer elements act from distal regions to mediate the transcription of genes. A novel combination of FISH and ChIP techniques may provide new insight into the mechanism by which enhancer elements exert their control. Application of the technique to the Hbb (encoding β-globin) locus control region (LCR) suggests that elements of the LCR may be in close proximity to the transcribed β-globin genes.

引用

页码：555 / 556

页数：2

共 16 条

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