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Medical progress: Age-related macular degeneration

被引：1185
作者：
Jager, Rama D. [1 ]
Mieler, William F. [1 ]
Miller, Joan W. [2 ]
机构：
[1] Univ Chicago, Sect Ophthalmol & Visual Sci, Dept Surg, Chicago, IL 60637 USA
[2] Harvard Univ, Sch Med, Dept Ophthalmol, Boston, MA USA
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2008年 / 358卷 / 24期
关键词：
D O I：
10.1056/NEJMra0801537
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Age-related macular degeneration is the leading cause of irreversible blindness in people 50 years of age or older in the developed world. This article reviews the clinical and histopathological features of age-related macular degeneration and its genetics and epidemiology and discusses current management options and research advances. Copyright © 2008 Massachusetts Medical Society. All rights reserved.
引用
收藏
页码：2606 / 2617
页数：12
相关论文
共 99 条
[11]   Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab [J].
Brantley, Milam A., Jr. ;
Fang, Amy M. ;
King, Jennifer M. ;
Tewari, Asheesh ;
Kymes, Steven M. ;
Shiels, Alan .
OPHTHALMOLOGY, 2007, 114 (12) :2168-2173
[12]  
Bressler NM, 2000, ARCH OPHTHALMOL-CHIC, V118, P488
[13]  
Bressler NM, 2003, ARCH OPHTHALMOL-CHIC, V121, P1621
[14]   THE GRADING AND PREVALENCE OF MACULAR DEGENERATION IN CHESAPEAKE BAY WATERMEN [J].
BRESSLER, NM ;
BRESSLER, SB ;
WEST, SK ;
FINE, SL ;
TAYLOR, HR .
ARCHIVES OF OPHTHALMOLOGY, 1989, 107 (06) :847-852
[15]  
Bressler NM, 1999, ARCH OPHTHALMOL-CHIC, V117, P1329
[16]   Racial differences in the prevalence of age-related macular degeneration - The Salisbury Eye Evaluation (SEE) Project [J].
Bressler, Susan B. ;
Munoz, Beatriz ;
Solomon, Sharon D. .
ARCHIVES OF OPHTHALMOLOGY, 2008, 126 (02) :241-245
[17]   Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: Results of a phase I clinical trial [J].
Campochiaro, PA ;
Nguyen, QD ;
Shah, SM ;
Klein, ML ;
Holz, E ;
Frank, RN ;
Saperstein, DA ;
Gupta, A ;
Stout, JT ;
Macko, J ;
DiBartolomeo, R ;
Wei, LL .
HUMAN GENE THERAPY, 2006, 17 (02) :167-176
[18]  
Casten Robin J, 2004, Curr Opin Ophthalmol, V15, P181, DOI 10.1097/01.icu.0000120710.35941.3f
[19]  
Chen LJ, 2006, MOL VIS, V12, P1536
[20]   Vitamin E and the age-related eye disease study supplementation for age-related macular degeneration [J].
Chew, EY ;
Clemons, T .
ARCHIVES OF OPHTHALMOLOGY, 2005, 123 (03) :395-396
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