Photodynamic activity of platinum(IV) chloride surface-modified TiO2 irradiated with visible light

被引：42

作者：

Janczyk, Agnieszka ^{[1
]}

Wolnicka-Glubisz, Agnieszka ^{[2
]}

Urbanska, Krystyna ^{[2
]}

Kisch, Horst

Stochel, Grazyna ^{[1
]}

Macyk, Wojciech ^{[1
]}

机构：

[1] Jagiellonian Univ, Fac Chem, Ingardena 3, PL-30060 Krakow, Poland

[2] Jagiellonian Univ, Fac Biochem Biophys & Biotechnol, Dept Biophys, PL-30349 Krakow, Poland

来源：

FREE RADICAL BIOLOGY AND MEDICINE | 2008年 / 44卷 / 06期

关键词：

reactive oxygen species; titanium dioxide; photocatalysis; phototoxicity; photodynamic therapy; mouse melanoma;

D O I：

10.1016/j.freeradbiomed.2007.12.019

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The visible light-induced phototoxicity of titanium dioxide modified with platinum(I-V) chloride complexes, [TiO2/PtCl4], was tested. In vitro experiments with the mouse melanoma cells (S-91) have demonstrated phototoxicity of the [TiO2/PtCl4] material. Detection of efficiently generated various reactive oxygen species ((OH)-O-center dot, O-2(center dot-), H2O2, O-1(2)) and also reactive chlorine species has proven the photodynamic activity of the tested material, induced by visible light (lambda > 455 nm). The cellular death (recognized as a necrosis) is a result of the cell membrane peroxidation. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：1120 / 1130

页数：11

共 67 条

[1] Use of Hoechst 33342 staining to detect apoptotic changes in bovine mononuclear phagocytes infected with Mycobacterium avium subsp paratuberculosis [J].

Allen, S ;

Sotos, J ;

Sylte, MJ ;

Czuprynski, CJ .

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2001, 8 (02) :460-464

[2]

*ATP DET KIT, 2003, MOL PROB PROD INF

[3]

BARR D, 2003, EPR EXPT TECHNIQUES

[4] PHOTOCHEMICAL GENERATION OF SUPEROXIDE RADICAL AND THE CYTO-TOXICITY OF PHTHALOCYANINES [J].

BENHUR, E ;

CARMICHAEL, A ;

RIESZ, P ;

ROSENTHAL, I .

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 1985, 48 (05) :837-846

[5] Application of the photocatalytic chemistry of titanium dioxide to disinfection and the killing of cancer cells [J].

Blake, DM ;

Maness, PC ;

Huang, Z ;

Wolfrum, EJ ;

Huang, J ;

Jacoby, WA .

SEPARATION AND PURIFICATION METHODS, 1999, 28 (01) :1-50

[6]

Bonnett R., 2000, Chemical Aspects of Photodynamic Therapy

[7] SPIN TRAPPING - ELECTRON-SPIN-RESONANCE PARAMETERS OF SPIN ADDUCTS [J].

BUETTNER, GR .

FREE RADICAL BIOLOGY AND MEDICINE, 1987, 3 (04) :259-303

[8] Photocatalytic and photoelectrochemical properties of titania-chloroplatinate(IV) [J].

Burgeth, G ;

Kisch, H .

COORDINATION CHEMISTRY REVIEWS, 2002, 230 (1-2) :41-47

[9] Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: Regulation by ultraviolet B [J].

Chakraborty, AK ;

Funasaka, Y ;

Slominski, A ;

Ermak, G ;

Hwang, J ;

Pawelek, JM ;

Ichihashi, M .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 1996, 1313 (02) :130-138

[10] RAPID COLORIMETRIC ASSAY FOR CELL-GROWTH AND SURVIVAL - MODIFICATIONS TO THE TETRAZOLIUM DYE PROCEDURE GIVING IMPROVED SENSITIVITY AND RELIABILITY [J].

DENIZOT, F ;

LANG, R .

JOURNAL OF IMMUNOLOGICAL METHODS, 1986, 89 (02) :271-277

← 1 2 3 4 5 6 7 →