Toward the Study of Trans-Disease Processes: A Novel Approach With Special Reference to the Study of Co-morbidity

被引:79
作者
Bickel, Warren K. [1 ]
Mueller, E. Terry [1 ]
机构
[1] Univ Arkansas Med Sci, Inst Psychiat Res, Addict Res Ctr, Fred & Louis Dierks Res Labs, Little Rock, AR 72205 USA
关键词
Trans-disease processes; co-morbidity; scale-free systems; delay discounting; cigarette smoking; schizophrenia; CIGARETTE-SMOKING; DISCOUNTING PROCESSES; DELAY; SMOKERS; IMPULSIVITY; ADDICTION; SYSTEMS; PROBABILITY; REWARDS; NEVER;
D O I
10.1080/15504260902869147
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
The objective of this article was to propose a novel approach, referred to as the study of trans-disease processes (TDPs), to the neuroscientific study of disease processes in general and to co-morbid diseases in particular. The features of this approach are outlined; one potential TDP-delay discounting, which may help account for the co-morbidity of cigarette smoking and schizophrenia-is explored; and the concept of TDPs is contrasted with the concept of endophenotypes. TDPs have the potential for a variety of positive impacts on science.
引用
收藏
页码:131 / 138
页数:8
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