A smooth operator for LPS responses

被引:44
作者
Godowski, PJ [1 ]
机构
[1] Genentech Inc, Dept Immunol, San Francisco, CA 94080 USA
[2] Genentech Inc, Dept Mol Biol, San Francisco, CA 94080 USA
关键词
D O I
10.1038/ni0605-544
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The function of CD14 in LPS signaling has remained enigmatic. Examination of the responses of cells and mice with defective CD14 shows that this molecule seems to modulate specific LPS recognition by TLR4.
引用
收藏
页码:544 / 546
页数:4
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