Imidazo[1,5-a]pyridine-3-ylidenes -: pyridine derived N-heterocyclic carbene ligands

被引：165

作者：

Burstein, C ^{[1
]}

Lehmann, CW ^{[1
]}

Glorius, F ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany

来源：

TETRAHEDRON | 2005年 / 61卷 / 26期

关键词：

ligand design; N-heterocyclic carbene; Suzuki-Miyaura cross-coupling;

D O I：

10.1016/j.tet.2005.03.115

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The ready synthesis of differently substituted 2H-imidazo[1,5-a]pyridin-4-ium bromides is reported. These salts are precursors for a new class of N-heterocyclic carbene ligands. As a consequence of their bicyclic geometry, these ligands are capable of influencing the coordination sphere of a carbene bound metal. The usefulness of these ligands was demonstrated in the palladium-catalyzed Suzuki-Miyaura cross-coupling, of sterically hindered aryl chlorides. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：6207 / 6217

页数：11

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