Alcohol associated liver disease 2020: A clinical practice guideline by the Italian Association for the Study of the Liver (AISF)

被引：31

作者：

Addolorato, Giovanni ^{[1
,2
]}

Abenavoli, Ludovico ^{[3
]}

Dallio, Marcello ^{[4
]}

Federico, Alessandro ^{[4
]}

Germani, Giacomo ^{[5
]}

Gitto, Stefano ^{[6
]}

Leandro, Gioacchino ^{[7
]}

Loguercio, Carmelina ^{[4
]}

Marra, Fabio ^{[6
,8
]}

Stasi, Elisa ^{[7
]}

机构：

[1] Univ Cattolica Sacro Cuore, Alcohol Use Disorder Unit, Div Internal Med, Gastroenterol & Hepatol Unit,A Gemelli Hosp, Rome, Italy

[2] Agostino Gemelli Hosp Fdn IRCCS, Rome, Italy

[3] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Catanzaro, Italy

[4] Univ Campania Luigi Vanvitelli, Dept Precis Med, Naples, Italy

[5] Padova Univ Hosp, Multivisceral Transplant Unit, Dept Surg Oncol & Gastroenterol, Padua, Italy

[6] Univ Florence, Dept Expt & Clin Med, Florence, Italy

[7] Natl Inst Gastroenterol S De Bellis Res Hosp, Castellana Grotte, Italy

[8] Univ Florence, Res Ctr Denothe, Florence, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2020年 / 52卷 / 04期

关键词：

Alcohol abstinence; Alcohol associated liver disease; Alcoholic hepatitis; Alcohol use disorder; Binge drinking; Liver damage; Liver transplantation; Psychosocial interventions; Treatment; PANCREATIC STELLATE CELLS; RANDOMIZED DOUBLE-BLIND; BINGE DRINKING; FATTY LIVER; WERNICKES ENCEPHALOPATHY; TRANSIENT ELASTOGRAPHY; HEPATIC HEMODYNAMICS; GENE-EXPRESSION; STRESS-RESPONSE; SCORING SYSTEM;

D O I：

10.1016/j.dld.2019.12.008

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Alcohol use disorder which includes alcohol abuse and dependence represents one of the leading risk factors for premature mortality in Europe and it is responsible of over 200 conditions, including neuropsychiatric disorders, chronic diseases, cancers and accidents leading to permanent disability. Alcohol use disorder represents the most common cause of liver damage in the Western world, with a wide spectrum of diseases ranging from steatosis, steatohepatitis, fibrosis, cirrhosis and cancer. The present clinical practice guidelines by the Italian Association for the Study of the Liver (AISF) are focused on the current knowledge about epidemiology, pathophysiology, clinical features, diagnosis and treatment of alcohol associated liver disease, aiming to provide practical recommendations on the management of this complex pathological condition. (C) 2019 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：374 / 391

页数：18

共 185 条

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