Characteristics and Treatment of Seizures in Patients with High-Grade Glioma: A Review

被引：37

作者：

Englot, Dario J. ^{[1
,2
]}

Berger, Mitchel S. ^{[2
,3
]}

Chang, Edward F. ^{[1
,2
]}

Garcia, Paul A. ^{[2
,4
]}

机构：

[1] Univ Calif San Francisco, Dept Neurol Surg, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, UCSF Epilepsy Ctr, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, UCSF Brain Tumor Res Ctr, San Francisco, CA 94143 USA

[4] Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA

来源：

NEUROSURGERY CLINICS OF NORTH AMERICA | 2012年 / 23卷 / 02期

关键词：

Anaplastic astrocytoma; Epilepsy; High-grade glioma; Glioblastoma; Seizure; DIAGNOSED BRAIN-TUMORS; TEMPORAL-LOBE EPILEPSY; QUALITY-OF-LIFE; ANTIEPILEPTIC DRUGS; GLIOBLASTOMA-MULTIFORME; PHASE-II; PROPHYLACTIC ANTICONVULSANTS; POSTOPERATIVE EPILEPSY; INTRACTABLE EPILEPSY; GLUTAMINE-SYNTHETASE;

D O I：

10.1016/j.nec.2012.01.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

High-grade gliomas (HGGs), including anaplastic astrocytoma and glioblastoma multiforme, are the most common primary brain tumors, and are often associated with seizures. Seizure control is a critical but often underappreciated goal in the treatment of patients harboring these malignant lesions. Patients with HGG who also have medically intractable seizures should be considered for a palliative resection guided by electrocorticography and functional mapping. Antiepileptic drugs remain the mainstay of seizure treatment in HGG, and antiepileptic medication should be started after a tumor-related seizure, but should not be used prophylactically in the absence of seizure activity.

引用

页码：227 / +

页数：11

共 92 条

[41] SEIZURES DURING THE IMMEDIATE POSTOPERATIVE PERIOD [J].

KVAM, DA ;

LOFTUS, CM ;

COPELAND, B ;

QUEST, DO .

NEUROSURGERY, 1983, 12 (01) :14-17

[42] SEIZURES IN THE MONGOLIAN GERBIL ARE RELATED TO A DEFICIENCY IN CEREBRAL GLUTAMINE-SYNTHETASE [J].

LAMING, PR ;

COSBY, SL ;

ONEILL, JK .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1989, 94 (02) :399-404

[43]

Lee JW, 2010, ARCH NEUROL-CHICAGO, V67, P336, DOI 10.1001/archneurol.2010.2

[44] PROPHYLACTIC ANTICONVULSANTS FOR PREVENTION OF IMMEDIATE AND EARLY POSTCRANIOTOMY SEIZURES [J].

LEE, ST ;

LUI, TN ;

CHANG, CN ;

CHENG, WC ;

WANG, DJ ;

HEIMBURGER, RF ;

LIN, CG .

SURGICAL NEUROLOGY, 1989, 31 (05) :361-364

[45] Seizure disorders in patients with brain tumors [J].

Liigant, A ;

Haldre, S ;

Oun, A ;

Linnamägi, Ü ;

Saar, A ;

Asser, T ;

Kaasik, AE .

EUROPEAN NEUROLOGY, 2001, 45 (01) :46-51

[46] Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study [J].

Lim, Daniel A. ;

Tarapore, Phiroz ;

Chang, Edward ;

Burt, Marlene ;

Chakalian, Lenna ;

Barbaro, Nicholas ;

Chang, Susan ;

Lamborn, Kathleen R. ;

McDermott, Michael W. .

JOURNAL OF NEURO-ONCOLOGY, 2009, 93 (03) :349-354

[47] The importance of drug adverse effects compared with seizure control for people with epilepsy - A discrete choice experiment [J].

Lloyd, A ;

McIntosh, E ;

Price, M .

PHARMACOECONOMICS, 2005, 23 (11) :1167-1181

[48]

Löscher W, 2002, CNS DRUGS, V16, P669

[49]

Lund M, 1952, ACTA PSYCH NEUROL SC, V81, P11

[50] Use of peri-operative anti-epileptic drugs in patients with newly diagnosed high grade malignant glioma: a single center experience [J].

Lwu, Shelly ;

Hamilton, Mark G. ;

Forsyth, Peter A. ;

Cairncross, J. Gregory ;

Parney, Ian F. .

JOURNAL OF NEURO-ONCOLOGY, 2010, 96 (03) :403-408

← 1 2 3 4 5 6 7 8 9 10 →