Allosteric modulation of neuronal nicotinic acetylcholine receptors

被引：27

作者：

Buisson, B ^{[1
]}

Bertrand, D ^{[1
]}

机构：

[1] Fac Med, Dept Physiol, CH-1211 Geneva 4, Switzerland

来源：

JOURNAL OF PHYSIOLOGY-PARIS | 1998年 / 92卷 / 02期

关键词：

nicotinic acetylcholine receptors; allosteric concepts; site-directed mutagenesis;

D O I：

10.1016/S0928-4257(98)80144-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The structure-function relationship of the neuronal nicotinic acetylcholine receptor is examined in the light of the allosteric concepts. Effects of site-directed mutagenesis as well as those caused by allosteric effector of the physiological and pharmacological receptor properties are discussed. ((C) Elsevier, Paris).

引用

收藏

页码：89 / 100

页数：12

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