Molecular Profiling: Moving Away from Tumor Philately

被引：54

作者：

Reis-Filho, Jorge S. ^{[1
]}

Weigelt, Britta ^{[2
]}

Fumagalli, Debora ^{[3
]}

Sotiriou, Christos ^{[3
]}

机构：

[1] Inst Canc Res, Mol Pathol Lab, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England

[2] London Res Inst, Signal Transduct Lab, Canc Res UK, London WC2A 3PX, England

[3] Univ Libre Brussels, Breast Canc Translat Res Lab, Inst Jules Bordet, B-1000 Brussels, Belgium

来源：

SCIENCE TRANSLATIONAL MEDICINE | 2010年 / 2卷 / 47期

关键词：

GENE-EXPRESSION PROFILES; BREAST-CANCER; NEOADJUVANT CHEMOTHERAPY; PROGNOSIS; SUBTYPES; METASTASIS; PREDICTORS; CARCINOMAS; SIGNATURES; TAMOXIFEN;

D O I：

10.1126/scitranslmed.3001329

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Despite the remarkable enhancements in breast cancer classification and characterization, an exhaustive comprehension of the underlying carcinogenic processes and an accurate prediction of its clinical behavior are yet to be achieved. On the wave of recent scientific advances and clinical findings, new cutting-edge technologies are poised to deliver an array of diverse molecular data that are expected to dramatically alter breast cancer diagnosis and treatment.

引用

页数：5

共 39 条

[1] Abramovitz Mark, 2007, Cancer Genomics & Proteomics, V4, P135
[2] Clinical application of the 70-gene profile: The MINDACT trial
Cardoso, Fatima
Van't Veer, Laura
Rutgers, Emiel
Loi, Sherene
Mook, Stella
Piccart-Gebhart, Martine J.
[J]. JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (05) : 729 - 735
[3] Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
Chin, Koei
DeVries, Sandy
Fridlyand, Jane
Spellman, Paul T.
Roydasgupta, Ritu
Kuo, Wen-Lin
Lapuk, Anna
Neve, Richard M.
Qian, Zuwei
Ryder, Tom
Chen, Fanqing
Feiler, Heidi
Tokuyasu, Taku
Kingsley, Chris
Dairkee, Shanaz
Meng, Zhenhang
Chew, Karen
Pinkel, Daniel
Jain, Ajay
Ljung, Britt Marie
Esserman, Laura
Albertson, Donna G.
Waldman, Frederic M.
Gray, Joe W.
[J]. CANCER CELL, 2006, 10 (06) : 529 - 541
[4] The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis
Cleator, Susan J.
Powles, Trevor J.
Dexter, Tim
Fulford, Laura
Mackay, Alan
Smith, Ian E.
Valgeirsson, Haukur
Ashworth, Alan
Dowsett, Mitch
[J]. BREAST CANCER RESEARCH, 2006, 8 (03)
[5] Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
Desmedt, Christine
Haibe-Kains, Benjamin
Wirapati, Pratyaksha
Buyse, Marc
Larsimont, Denis
Bontempi, Gianluca
Delorenzi, Mauro
Piccart, Martine
Sotiriou, Christos
[J]. CLINICAL CANCER RESEARCH, 2008, 14 (16) : 5158 - 5165
[6] Genome remodelling in a basal-like breast cancer metastasis and xenograft
Ding, Li
Ellis, Matthew J.
Li, Shunqiang
Larson, David E.
Chen, Ken
Wallis, Johnw.
Harris, Christopher C.
McLellan, Michael D.
Fulton, Robert S.
Fulton, Lucinda L.
Abbott, Rachel M.
Hoog, Jeremy
Dooling, David J.
Koboldt, Daniel C.
Schmidt, Heather
Kalicki, Joelle
Zhang, Qunyuan
Chen, Lei
Lin, Ling
Wendl, Michael C.
McMichael, Joshua F.
Magrini, Vincent J.
Cook, Lisa
McGrath, Sean D.
Vickery, Tammi L.
Appelbaum, Elizabeth
DeSchryver, Katherine
Davies, Sherri
Guintoli, Therese
Lin, Li
Crowder, Robert
Tao, Yu
Snider, Jacqueline E.
Smith, Scott M.
Dukes, Adam F.
Sanderson, Gabriel E.
Pohl, Craig S.
Delehaunty, Kim D.
Fronick, Catrina C.
Pape, Kimberley A.
Reed, Jerry S.
Robinson, Jody S.
Hodges, Jennifer S.
Schierding, William
Dees, Nathan D.
Shen, Dong
Locke, Devin P.
Wiechert, Madeline E.
Eldred, James M.
Peck, Josh B.
[J]. NATURE, 2010, 464 (7291) : 999 - 1005
[7] Concordance among gene-expression-based predictors for breast cancer
Fan, Cheng
Oh, Daniel S.
Wessels, Lodewyk
Weigelt, Britta
Nuyten, Dimitry S. A.
Nobel, Andrew B.
van't Veer, Laura J.
Perou, Charles M.
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 2006, 355 (06) : 560 - 569
[8] A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
Farmer, Pierre
Bonnefoi, Herve
Anderle, Pascale
Cameron, David
Wirapati, Pratyakasha
Becette, Veronique
Andre, Sylvie
Piccart, Martine
Campone, Mario
Brain, Etienne
MacGrogan, Gaetan
Petit, Thierry
Jassem, Jacek
Bibeau, Frederic
Blot, Emmanuel
Bogaerts, Jan
Aguet, Michel
Bergh, Jonas
Iggo, Richard
Delorenzi, Mauro
[J]. NATURE MEDICINE, 2009, 15 (01) : 68 - 74
[9] Stromal gene expression predicts clinical outcome in breast cancer
Finak, Greg
Bertos, Nicholas
Pepin, Francois
Sadekova, Svetlana
Souleimanova, Margarita
Zhao, Hong
Chen, Haiying
Omeroglu, Gulbeyaz
Meterissian, Sarkis
Omeroglu, Atilla
Hallett, Michael
Park, Morag
[J]. NATURE MEDICINE, 2008, 14 (05) : 518 - 527
[10] Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
Geyer, Felipe C.
Weigelt, Britta
Natrajan, Rachael
Lambros, Maryou B. K.
de Blase, Dario
Vatcheva, Radost
Savage, Kay
Mackay, Alan
Ashworth, Alan
Reis-Filho, Jorge S.
[J]. JOURNAL OF PATHOLOGY, 2010, 220 (05) : 562 - 573

← 1 2 3 4 →