The role of nutrition in viral disease

被引:20
作者
Beck, MA [1 ]
机构
[1] UNIV N CAROLINA, FRANK PORTER GRAHAM CHILD DEV CTR, CHAPEL HILL, NC 27599 USA
关键词
virus; malnutrition; nutrient deficiency; viral infection;
D O I
10.1016/S0955-2863(96)00132-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Malnutrition has been associated with a decrease in immune function. Impairment of immune function may lead to increased susceptibility to infection with viruses. Although there are many studies documenting the effect of host nutritional status on immune functions, fewer studies have examined the effect of host nutritional status on viral pathogenesis. This review examines the relationship between viral infection and the nutritional status of the the host, and documents that not only can the nutritional status of the host affect immune function, bur can have profound effects an, the virus itself One mechanism by which nutritional status affects the virulence of the viral pathogen involves selection for virulent viral genotypes. Other mechanisms remain to be elucidated. (C) Elsevier Science Inc. 1996
引用
收藏
页码:683 / 690
页数:8
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