Characterization of swine leptin (LEP) polymorphisms and their association with production traits

被引:63
作者
Kennes, YM
Murphy, BD
Pothier, F
Palin, MF
机构
[1] Agr & Agri Food Canada, Dairy & Swine Res & Dev Ctr, Lennoxville, PQ J1M 1Z3, Canada
[2] Univ Montreal, Fac Med Vet, Ctr Rech Reprod Anim, St Hyacinthe, PQ J2S 7C6, Canada
[3] Univ Laval, Dept Anim Sci, St Foy, PQ G1K 7P4, Canada
关键词
LEP gene; leptin; pig; polymorphism;
D O I
10.1046/j.1365-2052.2001.00768.x
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
Four polymorphisms in the swine leptin (LEP) gene were characterized and evaluated for association with economically important production traits in Yorkshire, Landrace and Duroc pigs. Our results show that these polymorphisms are generally of low frequency or are absent in pig populations. Two polymorphisms (A2845T and T3469C) may be associated (P<0.0078) with feed intake and growth rate traits in Landrace pigs.
引用
收藏
页码:215 / 218
页数:4
相关论文
共 8 条
[1]   Recombinant porcine leptin reduces feed intake and stimulates growth hormone secretion in swine [J].
Barb, CR ;
Yan, X ;
Azain, MJ ;
Kraeling, RR ;
Rampacek, GB ;
Ramsay, TG .
DOMESTIC ANIMAL ENDOCRINOLOGY, 1998, 15 (01) :77-86
[2]   Cloning and expression of the porcine obese gene [J].
Bidwell, CA ;
Ji, SQ ;
Frank, GR ;
Cornelius, SG ;
Willis, GM ;
Spurlock, ME .
ANIMAL BIOTECHNOLOGY, 1997, 8 (02) :191-206
[3]   RECOMBINANT MOUSE OB PROTEIN - EVIDENCE FOR A PERIPHERAL SIGNAL LINKING ADIPOSITY AND CENTRAL NEURAL NETWORKS [J].
CAMPFIELD, LA ;
SMITH, FJ ;
GUISEZ, Y ;
DEVOS, R ;
BURN, P .
SCIENCE, 1995, 269 (5223) :546-549
[4]  
KEMP RA, 1994, SWINE GENETICS HDB
[5]  
McNeel RL, 2000, J ANIM SCI, V78, P934
[6]   Backfat thickness in pigs is positively associated with leptin mRNA levels [J].
Robert, C ;
Palin, MF ;
Coulombe, N ;
Roberge, C ;
Silversides, FG ;
Benkel, BF ;
McKay, RM ;
Pelletier, G .
CANADIAN JOURNAL OF ANIMAL SCIENCE, 1998, 78 (04) :473-482
[7]  
STATISTICAL ANALYSES SYSTEM-SAS, 1989, SAS STAT US GUID VER, V2
[8]   A HinfI PCR-RFLP at the porcine leptin (LEP) gene [J].
Stratil, A ;
Peelman, L ;
VanPoucke, M ;
Cepica, S .
ANIMAL GENETICS, 1997, 28 (05) :371-372