Cobalt-catalyzed carbocyclization of o-Iodobenzaldehydes and o-Iodophenyl ketones with alkynes

被引：64

作者：

Chang, KJ ^{[1
]}

Rayabarapu, DK ^{[1
]}

Cheng, CH ^{[1
]}

机构：

[1] Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 21期

关键词：

D O I：

10.1021/ol035514s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of various omicron-iodobenzaldehydes and omicron-iodophenyl ketones with alkynes in the presence of Co(dppe)I-2 and Zn powder in acetonitrile at 80 degreesC afforded the corresponding indenols in moderate to excellent yields with exceedingly high regioselectivity. For most unsymmetrical alkynes tested, the carbocyclization gave a single regioisomer.

引用

页码：3963 / 3966

页数：4

共 36 条

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