A systematic look at an old problem

被引:219
作者
Kirkwood, Thomas B. L. [1 ]
机构
[1] Univ Newcastle, Integrated Syst Biol Ageing & Nutr, Inst Ageing & Hlth, Newcastle Upon Tyne NE4 6BE, Tyne & Wear, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1038/451644a
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:644 / 647
页数:4
相关论文
共 30 条
[1]   High oxidative damage levels in the longest-living rodent, the naked mole-rat [J].
Andziak, Blazej ;
O'Connor, Timothy P. ;
Qi, Wenbo ;
DeWaal, Eric M. ;
Pierce, Anson ;
Chaudhuri, Asish R. ;
Van Remmen, Holly ;
Buffenstein, Rochelle .
AGING CELL, 2006, 5 (06) :463-471
[2]   High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease [J].
Bender, A ;
Krishnan, KJ ;
Morris, CM ;
Taylor, GA ;
Reeve, AK ;
Perry, RH ;
Jaros, E ;
Hersheson, JS ;
Betts, J ;
Klopstock, T ;
Taylor, RW ;
Turnbull, DM .
NATURE GENETICS, 2006, 38 (05) :515-517
[3]   Cellular senescence: when bad things happen to good cells [J].
Campisi, Judith ;
di Fagagna, Fabrizio d'Adda .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (09) :729-740
[4]  
Esiri MM, 2001, LANCET, V357, P169
[5]  
Finch C., 2000, CHANCE DEV AGING
[6]   Stochastic and genetic factors influence tissue-specific decline in ageing C-elegans [J].
Herndon, LA ;
Schmeissner, PJ ;
Dudaronek, JM ;
Brown, PA ;
Listner, KM ;
Sakano, Y ;
Paupard, MC ;
Hall, DH ;
Driscoll, M .
NATURE, 2002, 419 (6909) :808-814
[7]   Positive correlation between mammalian life span and cellular resistance to stress [J].
Kapahi, P ;
Boulton, ME ;
Kirkwood, TBL .
FREE RADICAL BIOLOGY AND MEDICINE, 1999, 26 (5-6) :495-500
[8]   Towards an e-biology of ageing: integrating theory and data [J].
Kirkwood, TBL ;
Boys, RJ ;
Gillespie, CS ;
Proctor, CJ ;
Shanley, DP ;
Wilkinson, DJ .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2003, 4 (03) :243-249
[9]   Understanding the odd science of aging [J].
Kirkwood, TBL .
CELL, 2005, 120 (04) :437-447
[10]   Ageing - The old worm turns more slowly [J].
Kirkwood, TBL ;
Finch, CE .
NATURE, 2002, 419 (6909) :794-795