Engineering diversity into dynamic combinatorial libraries by use of a small flexible building block

被引:27
作者
Rowan, SJ [1 ]
Lukeman, PS [1 ]
Reynolds, DJ [1 ]
Sanders, JKM [1 ]
机构
[1] Univ Cambridge, Cambridge Ctr Mol Recognit, Chem Lab, Cambridge CB2 1EW, England
关键词
D O I
10.1039/a803935f
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Oligomerization of preorganized cinchona and xanthene building blocks to produce dynamic combinatorial libraries results in libraries with only a few components. Diversity is generated by the addition of semi-flexible ephedrine and cholate building blocks.
引用
收藏
页码:1015 / 1018
页数:4
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