An alternative stereoselective synthesis of trans(2R,3R)-3-hydroxypipecolic acid

被引：32

作者：

Haddad, M ^{[1
]}

Larchevêque, M ^{[1
]}

机构：

[1] CNRS, ENSCP, Organ Synth Lab, F-75005 Paris, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(01)00984-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The enantioselective synthesis of trans-(2R,3R)-3-hydroxypipecolic acid Ib is presented, starting from O-protected methyl mandelate as chiral source. The synthesis involved a regioselective intramolecular nucleophilic substitution of an azido epoxide as the key step. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：5223 / 5225

页数：3

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