A preliminary study of the analysis of explosives using packed-column supercritical fluid chromatography with atmospheric pressure chemical ionisation mass spectrometric detection

被引：21

作者：

McAvoy, Y

Dost, K

Jones, DC

Cole, MD

George, MW

Davidson, G

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Forens Sci Unit, Glasgow G1 1XW, Lanark, Scotland

[2] Univ Nottingham, Dept Chem, Nottingham NG7 2RD, England

来源：

FORENSIC SCIENCE INTERNATIONAL | 1999年 / 99卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

supercritical fluid chromatography; atmospheric-pressure chemical-ionisation mass spectrometry; explosives; nitroaromatics; nitrate esters; nitramines;

D O I：

10.1016/S0379-0738(98)00181-9

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

A packed-column supercritical fluid chromatographic (SFC) separation of explosive compounds hyphenated to atmospheric pressure chemical ionisation (APCI) mass spectrometric (MS) detection has been developed. Nitroaromatics, nitramines and nitrate esters can be resolved and identified, with theoretical limits of detection of approximately 100 ng on column. This represents a development over previously described gas chromatography-thermal energy analysis (GC-TEA), gas chromatography- electron capture detection (GC-ECD) and SFC methods for the analysis of explosives due to the molecular identification afforded by the mass spectrometry. Explosives in the combinations expected in commercially available mixtures can be separated and identified. A successful application to a laboratory trial simulating casework is described. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：123 / 141

页数：19

共 13 条

[1] QUALITATIVE SUPERCRITICAL FLUID CHROMATOGRAPHY FOURIER-TRANSFORM INFRARED-SPECTROSCOPY STUDY OF METHYLENE-CHLORIDE AND SUPERCRITICAL CARBON-DIOXIDE EXTRACTS OF DOUBLE-BASE PROPELLANT [J].