EFFICIENT ONE-POT SYNTHESIS OF β-UNSATURATED ISOXAZOL-5-ONES AND PYRAZOL-5-ONES UNDER ULTRASONIC IRRADIATION

被引：42

作者：

Ablajan, Keyume ^{[1
]}

Xiamuxi, Hainimu ^{[1
]}

机构：

[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 08期

关键词：

Isoxazol-5-one; 4-methyl-3-oxovalerate; one-pot synthesis; pyrazol-5-one; three-component reaction; DERIVATIVES; AGENTS; MCI-186; WATER;

D O I：

10.1080/00397911.2010.535949

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学];

摘要：

4-Arylmethylidene-3-isopropylisoxazol-5-ones and 4-arylmethylidene-1-phenyl-3-isopropylpyrazol-5-ones have been prepared from the reactions of hydroxylamine and phenylhydrazine with methyl 4-methyl-3-oxovalerate and aromatic aldehydes in an aqueous medium at room temperature in the presence of pyridine under ultrasonic irradiation. The simple and facile method produced products in good yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.

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页码：1128 / 1136

页数：9

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