RNAcentral: an international database of ncRNA sequences

被引:80
作者
Petrov, Anton I. [1 ]
Kay, Simon J. E. [1 ]
Gibson, Richard [1 ]
Kulesha, Eugene [1 ]
Staines, Dan [1 ]
Bruford, Elspeth A. [1 ]
Wright, Mathew W. [1 ]
Burge, Sarah [1 ]
Finn, Robert D. [1 ]
Kersey, Paul J. [1 ]
Cochrane, Guy [1 ]
Bateman, Alex [1 ]
Griffiths-Jones, Sam [2 ]
Harrow, Jennifer [3 ]
Chan, Patricia P. [4 ]
Lowe, Todd M. [4 ]
Zwieb, Christian W. [5 ]
Wower, Jacek [6 ]
Williams, Kelly P. [7 ]
Hudson, Corey M. [7 ]
Gutell, Robin [8 ]
Clark, Michael B. [9 ]
Dinger, Marcel [10 ]
Quek, Xiu Cheng [10 ]
Bujnicki, Janusz M. [11 ,12 ]
Chua, Nam-Hai [13 ]
Liu, Jun [13 ]
Wang, Huan [13 ]
Skogerbo, Geir [14 ,15 ,16 ]
Zhao, Yi [14 ,15 ,16 ]
Chen, Runsheng [14 ,15 ,16 ]
Zhu, Weimin [17 ,18 ]
Cole, James R. [19 ]
Chai, Benli [19 ]
Huang, Hsien-Da [20 ]
Huang, His-Yuan [20 ]
Cherry, J. Michael [21 ]
Hatzigeorgiou, Artemis [22 ]
Pruitt, Kim D. [23 ]
机构
[1] European Bioinformat Inst, European Mol Biol Lab, Cambridge CB10 1SD, England
[2] Univ Manchester, Fac Life Sci, Manchester M13 9PT, Lancs, England
[3] Wellcome Trust Sanger Inst, Cambridge CB10 1SD, England
[4] Univ Calif Santa Cruz, Dept Biomol Engn, Santa Cruz, CA 95064 USA
[5] Univ Texas Hlth Sci Ctr San Antonio, Dept Biochem, San Antonio, TX 78229 USA
[6] Auburn Univ, Dept Anim Sci, Auburn, AL 36849 USA
[7] Sandia Natl Labs, Livermore, CA 94551 USA
[8] Univ Texas Austin, Dept Integrat Biol, Austin, TX 78712 USA
[9] Univ Oxford, Dept Physiol Anat & Genet, MRC, Funct Genom Unit, Oxford OX1 3PT, England
[10] St Vincents Hosp, Garvan Inst Med Res, Kinghorn Ctr Clin Genom, Darlinghurst, NSW 2010, Australia
[11] Int Inst Mol & Cell Biol Warsaw, Lab Bioinformat & Prot Engn, PL-02109 Warsaw, Poland
[12] Adam Mickiewicz Univ, Inst Mol Biol & Biotechnol, Fac Biol, Lab Bioinformat, PL-61614 Poznan, Poland
[13] Rockefeller Univ, Plant Mol Biol Lab, New York, NY 10065 USA
[14] Chinese Acad Sci, Inst Biophys, Lab Noncoding RNA, Beijing 100101, Peoples R China
[15] Chinese Acad Sci, Inst Comp Technol, Beijing 100190, Peoples R China
[16] Chinese Acad Med Sci, Inst Basic Med Sci, Beijing, Peoples R China
[17] Peking Union Med Coll, Sch Basic Med, Beijing 100005, Peoples R China
[18] Taicang Inst Life Sci Informat, Suzhou 215400, Peoples R China
[19] Michigan State Univ, E Lansing, MI 48824 USA
[20] Natl Chiao Tung Univ, Dept Biol Sci & Technol, Inst Bioinformat & Syst Biol, Hsinchu, Taiwan
[21] Stanford Univ, Dept Genet, Palo Alto, CA 94304 USA
[22] Univ Thessaly, Dept Comp & Commun Engn, Volos 38221, Greece
[23] Natl Lib Med, Natl Ctr Biotechnol Informat, Bethesda, MD 20894 USA
基金
英国生物技术与生命科学研究理事会; 美国国家卫生研究院;
关键词
GENOME; EVOLUTION; GENCODE;
D O I
10.1093/nar/gku991
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The field of non-coding RNA biology has been hampered by the lack of availability of a comprehensive, up-to-date collection of accessioned RNA sequences. Here we present the first release of RNAcentral, a database that collates and integrates information from an international consortium of established RNA sequence databases. The initial release contains over 8.1 million sequences, including representatives of all major functional classes. A web portal (http://rnacentral.org) provides free access to data, search functionality, cross-references, source code and an integrated genome browser for selected species.
引用
收藏
页码:D123 / D129
页数:7
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